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首页> 外文期刊>International Journal of Nephrology >Transperitoneal Calcium Balance in Anuric Continuous Ambulatory Peritoneal Dialysis and Automated Peritoneal Dialysis Patients
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Transperitoneal Calcium Balance in Anuric Continuous Ambulatory Peritoneal Dialysis and Automated Peritoneal Dialysis Patients

机译：连续性非卧床动态腹膜透析和自动腹膜透析患者的腹​​膜钙平衡

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摘要

Backgrounds. Calcium (Ca) and bone metabolism in continuous ambulatory peritoneal dialysis (CAPD) and hemodialysis (HD) patients show a remarkable difference depending on dialysis modalities. The levels of serum Ca and phosphate (P) in HD patients fluctuate contributing to the intermittent and rapid removal of plasma solute unlike in CAPD. Characteristics of plasma solute transport in automated peritoneal dialysis (APD) patients are resembled with that in HD. The purpose of the present study was to examine the difference of transperitoneal Ca removal between APD and CAPD anuric patients.Subjects and Methods. Twenty-three APD anuric patients were enrolled in this study. Biochemical parameters responsible for transperitoneal Ca removal in 24-hour and 4-hour peritoneal effluents were analyzed on CAPD and APD.Results. Transperitoneal Ca removal on APD was smaller compared with that on CAPD. The Ca removal was related to the ultrafiltration during short-time dwell. Decrease of the Ca removal during NPD induced by short-time dialysate dwell caused negative or small Ca removal in APD patients. The levels of intact PTH were increased at the end of PET.Conclusion. It appears that short-time dwell and frequent dialysate exchanging might suppress the transperitoneal Ca removal in anuric APD patients.
机译：背景。持续非卧床腹膜透析（CAPD）和血液透析（HD）患者的钙（Ca）和骨代谢表现出显着差异，具体取决于透析方式。与CAPD不同，HD患者的血清Ca和磷酸盐（P）水平波动，导致血浆溶质的间歇性快速清除。自动腹膜透析（APD）患者的血浆溶质转运特征与HD相似。本研究的目的是探讨APD和CAPD无尿患者经腹膜Ca去除的差异。本研究招募了23名APD无尿患者。在CAPD和APD上分析了导致24小时和4小时腹膜流出液经腹膜钙去除的生化参数。与CAPD相比，APD的经腹膜Ca去除较小。 Ca的去除与短时停留期间的超滤有关。短期透析液停留引起的NPD期间Ca去除的减少导致APD患者的Ca去除为负或小。 PET结束时完整的PTH水平升高。结论。似乎短时间的停留和频繁的透析液交换可能会抑制无尿APD患者的经腹膜Ca去除。

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