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Prevalence and Predictors of Urinary Tract Infections among Children with Cerebral Palsy in Makurdi, Nigeria

机译:尼日利亚马库尔迪市儿童脑瘫患儿尿路感染的患病率和预测因素

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Background. Children with cerebral palsy (CP) are prone to urinary tract infection (UTI). Methods/Objectives. The prevalence and the predictors of UTI among children with CP were compared to age- and sex-matched children without CP at Federal Medical Centre, Makurdi, Nigeria, from December 2011 to May 2013. Results. The age range was between 2 and 15 years with a mean age of years including 30 males and 22 females. UTI was confirmed in 20 (38.5%) CP children compared to 2 children (3.8%) without CP ( value 0.000). Among CP children, Escherichia coli was the commonest organism isolated in 9 (9/20, 45.0%), Streptococcus faecalis in 4 (20.0%), and Staphylococcus aureus in 3 (15%), while both Proteus spp. and Klebsiella spp. were isolated in 2 children (10.0%) each. Escherichia coli was also found in the 2 children without CP. All the organisms were resistant to cotrimoxazole, nalidixic acid, nitrofurantoin, and amoxiclav, while they were 100% sensitive to ceftriaxone and the quinolones. In a univariate regression analysis, only moderate to severe gross motor dysfunction predicted the risk of UTI (, 95% CI, 2.27–1324.00, value 0.014). Conclusion. Efforts should be put in place to aid mobility among CP children in order to reduce the risk of UTI.
机译:背景。脑性瘫痪(CP)患儿容易发生尿路感染(UTI)。方法/目标。 2011年12月至2013年5月,在尼日利亚马库尔迪联邦医疗中心,对患有CP的儿童与未患有CP的年龄和性别相匹配的儿童的患病率和预测因素进行了比较。结果。年龄范围为2至15岁,平均年龄为30岁,男性22位,女性。在20名(38.5%)的CP儿童中确认了UTI,而没有CP的2名儿童(3.8%)被确认(价值0.000)。在CP儿童中,大肠杆菌是分离的最常见的生物,占9(9/20,45.0%),粪便链球菌占4(20.0%),金黄色葡萄球菌占3(15%),而变形杆菌属。和克雷伯菌属。分别被隔离在2个孩子中(10.0%)。在没有CP的2名儿童中也发现了大肠杆菌。所有的生物体对科曲美唑,萘啶酸,硝基呋喃妥因和阿莫西拉夫都有抗性,而它们对头孢曲松和喹诺酮类药物具有100%的敏感性。在单因素回归分析中,只有中度至重度总体运动功能障碍可预测发生UTI的风险(95%CI,2.27-11324.00,值0.014)。结论。应努力帮助CP儿童之间的流动,以减少UTI的风险。

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