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首页> 外文期刊>International Journal of Pediatrics >Retrospective Cohort Analysis of Central Line Associated Blood Stream Infection following Introduction of a Central Line Bundle in a Neonatal Intensive Care Unit
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Retrospective Cohort Analysis of Central Line Associated Blood Stream Infection following Introduction of a Central Line Bundle in a Neonatal Intensive Care Unit

机译：在新生儿重症监护病房中引入中央线束后，对中央线相关血流感染的回顾性队列分析

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Background. Central Line Associated Bloodstream Infections (CLABSI) constitute a leading cause of morbidity and mortality in neonatal populations. There has been an overwhelming increase in the use of evidence-based care practices, also known as bundles, in the reduction of these infections. In this report, rates of CLABSI and central line utilisation were examined following the introduction of a central line bundle in our Neonatal Intensive Care Unit (NICU) at the Canberra Hospital. Methods. The research undertaken was a retrospective cohort study in which newborn infants admitted to the Canberra Hospital NICU between January 2011 and December 2016 and had a central line inserted were included in the study. Data regarding central line days, bed days, infection rates, and patient demographics were collected before and after the introduction of an intervention bundle. CLABSI rates were calculated per 1,000 central line days for before (2011-2013) and after (2014-2016) the introduction of the bundle. The postintervention period was retrospectively analysed for compliance, with data regarding the completion of maintenance forms and insertion forms collected. Results. Overall, the results showed a significant decrease in CLABSI rates from 8.8 per 1,000 central line days to 4.9 per 1,000 central line days in the intervention period (p<0.001). Central line utilisation ratio (CLUR ratio of central line days to bed days) was also reduced between pre- and postintervention periods, from 0.177 (4414/25013) to 0.13 (3633/27384; p<0.001). Compliance to insertion forms and maintenance forms was observed to increase within the intervention period. Conclusion. The implementation of a central line bundle was effective in reducing both CLABSI rates and dwell time (CLUR) for central venous catheters.
机译：背景。中线相关血流感染（CLABSI）是新生儿人群发病和死亡的主要原因。在减少这些感染方面，以证据为基础的护理实践（也称为捆绑疗法）的使用已大大增加。在本报告中，我们在堪培拉医院的新生儿重症监护室（NICU）中引入了中心线束之后，检查了CLABSI和中心线利用率。方法。这项研究是一项回顾性队列研究，该研究包括2011年1月至2016年12月在堪培拉医院新生儿重症监护病房（NICU）住院并插入中心线的新生儿。在引入干预捆绑之前和之后，收集有关中心线日，就诊日，感染率和患者人口统计数据。在引入捆绑软件之前（2011-2013年）和之后（2014-2016年），每1000个中心线天计算一次CLABSI费率。回顾性分析干预后期间的服从情况，并收集有关填写的维护表格和插入表格的数据。结果。总体而言，结果显示，干预期间CLABSI率从每1000个中线日8.8天显着降低到每1000个中线日4.9天（p <0.001）。在干预前后，中心线利用率（中心线天数与就寝天数的CLUR比）也从0.177（4414/25013）降低到0.13（3633/27384; p <0.001）。在干预期内，遵守插入表格和维护表格的情况有所增加。结论。中心线束的实施可有效降低中心静脉导管的CLABSI率和驻留时间（CLUR）。

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