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首页> 外文期刊>International Journal of Pediatrics >Vitamin D Status and Associated Factors in Neonates in a Resource Constrained Setting
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Vitamin D Status and Associated Factors in Neonates in a Resource Constrained Setting

机译：资源受限环境下新生儿的维生素D状况和相关因素

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摘要

Vitamin D deficiency (VDD) is emerging as a serious public health problem globally; however due to lack of resources, vitamin D levels are not routinely measured among neonates. The study was conducted to determine vitamin D levels in neonates and factors associated with the same. A cross-sectional study was conducted among neonates admitted at neonatal ward of a tertiary care hospital. Means and proportions were calculated from summarized data in frequency tables. Chi square test was used to determine association between vitamin D and various associated factors such as sex, infant birth weight, gestation age, parity of the mother, maternal age, and HIV status of the mother. A total of 170 neonates were studied, out of which 80% had vitamin D deficiency. Neonates born to HIV-infected mothers were significantly less likely to have vitamin D deficiency (OR 0.21, 95% CI 0.06 – 0.77, p = 0.009). Subgroup analysis revealed the association to be stronger in terms neonates (p = 0.005). The association was not observed among preterm newborns. The prevalence of vitamin D deficiency in neonates was observed to be very high and needs more attention.
机译：维生素D缺乏症（VDD）在全球范围内正成为一个严重的公共卫生问题。然而，由于缺乏资源，新生儿无法常规测量维生素D的水平。进行该研究以确定新生儿中的维生素D水平及其相关因素。在三级医院新生儿病房住院的新生儿中进行了横断面研究。从频率表中的汇总数据计算出平均值和比例。卡方检验用于确定维生素D与各种相关因素之间的关联，例如性别，婴儿出生体重，妊娠年龄，母亲的同等性，母亲的年龄和母亲的HIV状况。共研究了170名新生儿，其中80％有维生素D缺乏症。感染了HIV的母亲所生的新生儿维生素D缺乏的可能性大大降低（OR 0.21，95％CI 0.06 – 0.77，p = 0.009）。亚组分析显示，该关联在新生儿方面更强（p = 0.005）。在早产儿中未观察到这种关联。新生儿中维生素D缺乏症的患病率很高，需要引起更多注意。

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