• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Neonatal Screening >A Novel Approach to Critical Congenital Heart Disease (CCHD) Screening at Moderate Altitude
【24h】

A Novel Approach to Critical Congenital Heart Disease (CCHD) Screening at Moderate Altitude

机译：在中等海拔条件下筛查危重先天性心脏病（CCHD）的新方法

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The American Academy of Pediatrics (AAP) has endorsed Critical Congenital Heart Disease (CCHD) screening using pulse oximetry nationwide, but, however, acknowledges that altitude may impact failure rates and alternative algorithms may be required at high altitudes. We therefore evaluated a modified screening protocol at an altitude of 6200 feet with the hypothesis that modifications could decrease failure rates. We evaluated 2001 well, newborn infants ?￠???￥35 weeks gestation using a modified protocol, which included a lower saturation cutoff for the first screen (85% instead of the AAP recommended 90%) and an oxygen hood intervention between the first two screens. Using our modified screening algorithm, we found a 0.3% failure rate, which was similar to the 0.2% sea-level rate and statistically different from the 1.1% rate identified in a recent study at similar altitude. Had the AAP protocol been used, the failure rate would have increased to 0.8%, which is similar to prior reports near this altitude. Echocardiograms were performed on failing newborns with no CCHD identified. A Birth Defects Registry Database review demonstrated one newborn with CCHD was missed after meeting AAP passing criteria. Overall, this study demonstrates that an alternative algorithm can be implemented at moderate altitude with decreased failure rate and comparable false negative rate.
机译：美国儿科学会（AAP）已在全国范围内认可了使用脉搏血氧仪进行的关键先天性心脏病（CCHD）筛查，但是，该研究承认，海拔高度可能会影响故障率，并且在高海拔地区可能需要其他算法。因此，我们评估了在6200英尺高度的改良筛选方案，其假设是改良可以降低失败率。我们采用改良的方案评估了2001年出生的婴儿，妊娠≥35周，其中包括第一次筛查的饱和度较低（85％而不是AAP建议的90％），并且在第一次筛查之间进行了氧气罩干预两个屏幕。使用改进的筛选算法，我们发现失败率为0.3％，这与0.2％的海平面率相似，并且与最近在类似海拔高度的研究中确定的1.1％的统计学上存在差异。如果使用AAP协议，则故障率将增加到0.8％，这与以前在该高度附近的报告相似。对未确诊CCHD的衰竭新生儿进行超声心动图检查。一项出生缺陷登记数据库的审查表明，一名符合CCHD的新生儿在符合AAP通过标准后被错过了。总的来说，这项研究表明，可以在中等海拔高度实施另一种算法，从而降低故障率并降低假阴性率。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号