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Quality assessment and phytochemical analysis of Clerodendrum serratum roots

机译:锯缘青蟹根的质量评估和植物化学分析

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Objectives: Clerodendrum serratum (L.) Moon. (Verbenaceae) commonly known as bharangi is an important medicinal plant growing in India having traditional value to treat pain, inflammation, rheumatism, respiratory disorders and fever. The aim of present study is to develop pharmacognostical, physicochemical and phytochemical parameters for quality assessment of Clerodendrum serratum roots (CSR). Methods: The roots of C. serratum were evaluated for pharmacognostical, physicochemical parameters such as ash values (total ash, acid insoluble ash and water soluble ash), extractive values (alcohol and water soluble), moisture content, crude fiber content and foaming index according to WHO guidelines on quality control methods for medicinal plant materials. The phytochemical analysis was performed using chemical tests, ultraviolet spectroscopy, thin layer chromatography and quantitative estimation of secondary phytoconstituents. Results: The pharmacognostical and physicochemical parameters evaluated for the roots were found in compliance with the Pharmacopoeial standards of crude drug. The qualitative and quantitative phytochemical analysis of methanolic extract of CSR showed presence of phenolics, flavonoids, saponins and carbohydrates. Conclusion: The present investigation will be helpful for the identification and quality control of CSR.
机译:目标:锯齿羊齿月亮。马鞭草科(Verbenaceae)通常在印度生长,是一种重要的药用植物,在印度具有治疗疼痛,炎症,风湿病,呼吸系统疾病和发烧的传统价值。本研究的目的是开发药理学,理化和植物化学参数,以用于评估锯缘青蟹根(CSR)的质量。方法:对锯齿衣藻的根进行药理学,理化参数的评估,例如灰分值(总灰分,酸不溶性灰分和水溶性灰分),提取值(酒精和水溶性),水分含量,粗纤维含量和发泡指数根据WHO关于药用植物材料质量控制方法的指南。使用化学测试,紫外光谱法,薄层色谱法和次级植物成分的定量估计进行植物化学分析。结果:发现根的药理学和理化参数符合原料药的药典标准。对CSR甲醇提取物的定性和定量植物化学分析表明,存在酚类,类黄酮,皂角苷和碳水化合物。结论:本研究将有助于企业社会责任的识别和质量控制。

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