...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Pharmaceutical Sciences and Research >COMPARISON OF SURGICAL SITE INFECTION RATE BETWEEN ANTIBACTERIAL COATED SURGICAL SUTURE AND CONVENTIONAL SUTURE: A RANDOMIZED CONTROLLED SINGLE CENTRE STUDY FOR PREVENTIVE MEASURE OF POSTOPERATIVE INFECTION
【24h】

COMPARISON OF SURGICAL SITE INFECTION RATE BETWEEN ANTIBACTERIAL COATED SURGICAL SUTURE AND CONVENTIONAL SUTURE: A RANDOMIZED CONTROLLED SINGLE CENTRE STUDY FOR PREVENTIVE MEASURE OF POSTOPERATIVE INFECTION

机译：抗菌涂层手术缝合线与常规缝合线的手术部位感染率比较：随机控制的单中心研究，用于预防性手术后感染

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The main objective of this study is to compare the reduction rate of surgical site infection (SSI) between Triclosan coated (TC) and conventional surgical (CS) suture postoperatively. Surgical site infection (SSI) can be presented as a major challenge for people in the sense of mortality and morbidity mostly in developing countries. The result of SSI with antibacterial suture in developed countries have been already reported; however, these interventions have been studied very little in those developing and underdeveloped countries where lifestyle and the hospital facility plays a major role in infection. A single-center randomized controlled trial was conducted at Civil Hospital Aizawl, Mizoram, India. A total of 110 patients were recruited for the study with a 1:1 ratio in both TC and CS. Superficial SSI was assessed as primary outcomes according to the Centre for Disease Control (CDC) guidelines until 30 days. Secondary outcomes also measured for 1supst/sup and 3suprd/sup days of surgery. Sutures were tested in laboratory condition for their antibacterial activity before use in surgery. Zone of inhibition (mm), 5.67 ± 0.2, 5.25 ± 0.25 and 4.75 ± 0.25 (Mean ± SEM) against E. coli, B. Subtilis, and P. aeruginosa with TC and no inhibition were observed with CS respectively. The clinical study shows 5 infections in CS and zeroes infection in TC after 1supst/sup, 3rd, and 30 days observations. The studies confirm the antibacterial efficacy of TC and also reduce the infection rate in the patient.
机译：这项研究的主要目的是比较术后三氯生涂膜（TC）和常规外科手术（CS）缝合线之间的手术部位感染（SSI）减少率。手术部位感染（SSI）可能是人们主要在发展中国家的死亡率和发病率方面面临的主要挑战。已经报道了发达国家使用抗菌缝合进行SSI的结果;但是，在生活方式和医院设施在感染中起主要作用的那些发展中国家和不发达国家中，对这些干预措施的研究很少。在印度米佐拉姆邦的Aizawl民间医院进行了一项单中心随机对照试验。总共招募了110名患者，其中TC和CS的比例为1：1。根据疾病控制中心（CDC）指南，浅表性SSI被评估为主要结局，直至30天。在手术的第1天和第3天也测量了次要结局。在手术中使用之前，在实验室条件下对缝合线的抗菌活性进行了测试。用TC抑制大肠杆菌，枯草芽孢杆菌和铜绿假单胞菌的抑制区（mm），5.67±0.2、5.25±0.25和4.75±0.25（平均值±SEM），而用CS分别未见抑制作用。临床研究显示，在第1天，第3天和第30天观察到CS感染5例，TC感染零。这些研究证实了TC的抗菌功效，也降低了患者的感染率。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号