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首页> 外文期刊>International Journal of Pharmaceutical Sciences and Research >EVALUATION OF PHYTOCHEMICALS AND IN VITRO PHARMACOLOGICAL ACTIVITY OF ACACIA SINUATA PLANT LEAVES
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EVALUATION OF PHYTOCHEMICALS AND IN VITRO PHARMACOLOGICAL ACTIVITY OF ACACIA SINUATA PLANT LEAVES

机译：厚荚相思叶片的生化评价和体外药理活性。

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Objective: The present work is aimed to screen phytochemicals, in vitro antimicrobial and antioxidant activity of the non polar and polar extracts of Acacia sinuata. Methods: Leaves of Acacia sinuata– were collected, dried and powdered. The powdered material is subjected to soxhlet extraction using various polar to non polar solvents and allowed for evaporation. The crude extracts thus obtained were used for further screening of phytochemicals, in vitro antimicrobial activity and antioxidant activities. Results: Phytochemical evaluation of Acacia sinuata proved that most of the secondary metabolites are extracted in polar solvents than non polar solvent like hexane. All the extracts of the Acacia sinuata possess significant amount of phenols and flavonoids and they also showed antimicrobial and antioxidant activity. Out of all the extracts of Acacia sinuata, methanol extracts showed better antibacterial, antifungal activity and antioxidant activity. Conclusion: The present work concluded that the methanol extract of Acacia sinuata was useful to develop new plant based dugs against various pathogenic bacteria as well as fungal species.
机译：目的：本研究旨在筛选中华相思非极性和极性提取物的植物化学成分，体外抗菌和抗氧化活性。方法：收集阿拉伯树胶（Acacia sinuata）的叶子，干燥并撒粉。使用各种极性至非极性溶剂对粉末状材料进行索氏提取，然后蒸发。由此获得的粗提取物用于进一步筛选植物化学物质，体外抗微生物活性和抗氧化活性。结果：相思树的植物化学评估证明，大多数次生代谢产物是在极性溶剂中提取的，而不是非极性溶剂（如己烷）。阿拉伯金合欢的所有提取物均含有大量的酚和类黄酮，它们还显示出抗菌和抗氧化活性。在金合欢的所有提取物中，甲醇提取物表现出更好的抗菌，抗真菌活性和抗氧化活性。结论：目前的工作得出结论，金合欢的甲醇提取物可用于开发针对各种病原细菌和真菌物种的新的植物基挖掘物。

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