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首页> 外文期刊>International Journal of Preventive Medicine >HEPATIC ARTERY AND PORTAL VEIN DOPPLER INDEXES IN NON-ALCOHOLIC FATTY LIVER DISEASE BEFORE AND AFTER TREATMENT TO PREVENT UNNECESSARY HEALTH CARE COSTS
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HEPATIC ARTERY AND PORTAL VEIN DOPPLER INDEXES IN NON-ALCOHOLIC FATTY LIVER DISEASE BEFORE AND AFTER TREATMENT TO PREVENT UNNECESSARY HEALTH CARE COSTS

机译：非酒精性脂肪肝疾病治疗前后的肝动脉和门静脉多普勒指数，以预防不必要的医疗费用

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Background: We tested whether hepatic hemodynamics’ assessed by Doppler ultrasonography can be a predictor of response to therapy in patients with non-alcoholic fatty liver disease (NAFLD) to prevent further unnecessary diagnostic tests and interventions.Methods: Forty eight consecutive patients affected by NAFLD, who refered to some clinics in Tabriz, Iran between 2009 and 2011 were included in the study. Response to therapy was assessed by decrease in liver enzyme levels. Three liver Doppler parameters (hepatic artery resistance index, hepatic artery pulsatility index [PI] and portal vein waveform [PVW]) were analysed in all subjects who showed a decrease in liver function tests results. Wilcoxon and paired students t -test were used for analysis.Results: Forty eight subjects with NAFLD were included in the study during 21 months, out of which 22 (39.1% male - mean age: 37.6±8.3) responded to the treatment and formed the basis of this study. Mean hepatic artery RI increased significantly from 0.60±0.07 to 0.83±0.27 before and after treatment, however, there was no significant differences between hepatic artery PI or PVW.Conclusions: Increase in hepatic artery RI assessed by Doppler ultrasound may provide information on improvement of NAFLD in patients during the course of therapy.
机译：背景：我们测试了通过多普勒超声检查评估的肝血流动力学是否可以预测非酒精性脂肪肝疾病（NAFLD）患者对治疗的反应，以防止进一步不必要的诊断测试和干预。方法：连续48例受NAFLD影响的患者该研究包括2009年至2011年间在伊朗大不里士提到的一些诊所的人。通过降低肝酶水平评估对治疗的反应。在所有显示肝功能测试结果均下降的受试者中，分析了三个肝多普勒参数（肝动脉阻力指数，肝动脉搏动指数[PI]和门静脉波形[PVW]）。结果：在21个月内纳入了48例NAFLD受试者，其中22例（男性的平均年龄为39.1％，平均年龄：37.6±8.3）对治疗作出反应并形成本研究的基础。治疗前和治疗后平均肝动脉RI从0.60±0.07显着增加到0.83±0.27，但是在肝动脉PI或PVW之间没有显着差异。结论：多普勒超声评估肝动脉RI的增加可能提供改善的信息患者在治疗过程中的NAFLD。

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