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首页> 外文期刊>International Journal of Research in Medical Sciences >Central nervous system tumors: a histopathological study
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Central nervous system tumors: a histopathological study

机译：中枢神经系统肿瘤：组织病理学研究

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Background: Brain tumors can originate in almost any type of tissue, cell or mixture of cell types in the brain or spinal cord. Tumors in different areas of the central nervous system may be treated differently and have a different prognosis. Methods: In the period between 2011-2015, we studied on 59 patients diagnosed with CNS tumors according to the World Health Organization's diagnostic criteria. Patient data were retrieved from the archives of the department of Pathology, Sardar Patel Medical College, Bikaner. The diagnosis in all the cases were made on hematoxylin & eosin stained slides of processed tissue. Results: Patients ages ranged from 3.5-65 years with a mean age of 41.2 years and a male to female ratio of 1.8:1. Majority of tumors had intracranial location (55 cases, 93.23%). 91.5% tumors were solid in consistency. Frontal lobe (37.3%) was the predominant affected region. Most tumors were originated from neuroepithelium (67.8%) followed by meninges (22.03%). When examining the data pertaining to specific types of tumors, most frequent type of CNS tumors was astrocytoma (31 cases, 52.5%), followed by meningioma (13 cases, 22%). Conclusion: The most frequent type of CNS tumours in this study was astrocytoma, followed by meningioma. Males are at much higher risk of developing CNS tumour in comparison to females (1.8:1). WHO Grade IV lesions were more common in our institutional set up. The exact histological diagnosis of CNS tumors is essential to predict the prognostic factors.
机译：背景：脑肿瘤可起源于脑或脊髓中几乎任何类型的组织，细胞或细胞混合物。中枢神经系统不同区域的肿瘤可能会受到不同的对待，预后也不同。方法：根据世界卫生组织的诊断标准，在2011年至2015年期间，我们对59名被诊断患有CNS肿瘤的患者进行了研究。患者数据来自Bikaner的Sardar Patel医学院病理学系的档案。所有病例的诊断均基于苏木精和曙红染色的经处理的组织切片。结果：患者年龄为3.5-65岁，平均年龄为41.2岁，男女之比为1.8：1。多数肿瘤位于颅内（55例，93.23％）。 91.5％的肿瘤一致。额叶（37.3％）是主要的受累区域。大多数肿瘤起源于神经上皮（67.8％），其次是脑膜（22.03％）。检查有关特定类型肿瘤的数据时，中枢神经系统肿瘤最常见的类型是星形细胞瘤（31例，52.5％），其次是脑膜瘤（13例，22％）。结论：本研究中最常见的中枢神经系统肿瘤类型是星形细胞瘤，其次是脑膜瘤。与女性相比，男性患中枢神经系统肿瘤的风险要高得多（1.8：1）。 WHO的IV级病变在我们的机构中​​更为常见。中枢神经系统肿瘤的准确组织学诊断对于预测预后因素至关重要。

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