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首页> 外文期刊>International Journal of Research in Medical Sciences >Study of various causes of defaulter among tuberculosis patients under revised national tuberculosis control programme: a prospective analysis of 5235 tuberculosis patients
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Study of various causes of defaulter among tuberculosis patients under revised national tuberculosis control programme: a prospective analysis of 5235 tuberculosis patients

机译:在修订的国家结核病控制计划下研究结核病患者各种违法行为的原因:对5235例结核病患者的前瞻性分析

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Background: The world health organization (WHO) declared tuberculosis (TB) a global public health emergency in 1993 and since then intensified its efforts to control the disease worldwide. Poor compliance with tuberculosis (TB) treatment has reportedly been cited as one of the major obstacles which have led to spread of TB and development of multi-drug resistant and extensively drug resistant tuberculosis. The objective is to investigate factors contributing to treatment non-adherence among patients on TB treatment, the results of which might help us to design intervention that would promote compliance. Methods: All TB patients admitted to the Institute were interviewed regarding the past history of anti-tuberculosis treatment (AKT). As per the revised national tuberculosis control programme (RNTCP) guidelines, we defined defaulter as patient who had interrupted AKT for more than 2 months. All the interviewed patients had taken AKT at RNTCP DOT sites. Patient who has taken AKT from private institute were excluded. All the defaulted patients were then interviewed in details. In addition to the personal and socio-demographic data, treatment history was recorded in details along with reasons for stopping treatment. Results: Among 5235 TB patients, 405 (7.7%) were found to have a past history of AKT interruption. The highest number of treatment interrupters were in the age group 21 to 50 years (n=309), constituting nearly 76.29% of all the patients studied. The most common reason stated was AKT-induced side effects (42.2%) a feeling of early improvement (33.3%) and followed by migration for work (9.6%). Conclusions: Present study concludes that the most common cause of defaulters amongst tuberculosis patients are adverse effects, feeling of early improvement and migration.
机译:背景:世界卫生组织(WHO)在1993年宣布结核病(TB)为全球公共卫生紧急事件,此后加大了在全球范围内控制该疾病的努力。据报道,对结核病(TB)治疗的依从性差是导致结核病蔓延和发展多药耐药和广泛耐药结核病的主要障碍之一。目的是研究导致结核病患者治疗不依从性的因素,其结果可能有助于我们设计可提高依从性的干预措施。方法:对所有入院的结核病患者进行抗结核治疗(AKT)的既往史采访。根据修订的国家结核病控制计划(RNTCP)指南,我们将默认者定义为中断AKT超过2个月的患者。所有接受采访的患者均在RNTCP DOT站点接受了AKT。从私人机构接受AKT的患者被排除在外。然后对所有违约患者进行详细访谈。除了个人和社会人口统计学数据外,还详细记录了治疗史以及停止治疗的原因。结果:在5235 TB患者中,有405名(7.7%)有AKT中断史。治疗中断者的最高数量是21至50岁年龄段(n = 309),占所有研究患者的近76.29%。陈述的最常见原因是AKT引起的副作用(42.2%)以及早期改善的感觉(33.3%),其次是工作迁移(9.6%)。结论:本研究得出结论,在结核病患者中,最常见的导致失明的原因是不良反应,早期感觉改善和迁移。

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