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首页> 外文期刊>International Journal of Research in Medical Sciences >Comparison of the efficacy of combined epidural anesthesia with general anaesthesia alone to attenuate hemodynamic responses and perioperative analgesia in laparoscopic cholecystectomy patients
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Comparison of the efficacy of combined epidural anesthesia with general anaesthesia alone to attenuate hemodynamic responses and perioperative analgesia in laparoscopic cholecystectomy patients

机译：腹腔镜胆囊切除术患者联合硬膜外麻醉与单纯全身麻醉减弱血液动力学反应和围手术期镇痛的疗效比较

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Background: The aim of the study was to compare the efficacy of combined GA-Epidural Anesthesia (CEGA) with GA alone to attenuate hemodynamic responses and perioperative analgesia. Method: Authors conducted a prospective, randomized, double blind study, in which 60 patients undergoing laparoscopic cholecystectomy. Group A received (n=30) received GA and Group B (n=30) received combined GA and Epidural Anaesthesia (CEGA). Authors analyzed the effect of combined epidural general anaesthesia as compared to plain general anaesthesia with regard to hemodynamic parameters (heart rate, systolic and diastolic blood pressure), intraoperative anaesthetic requirement (intraoperative requirement of propofol), recovery score and postoperative analgesia (VAS score). Results : Authors found significant decrease in the heart rate, systolic and diastolic blood pressure in response to stress response to pneumoperitoneum in combined epidural general anaesthesia (CEGA) group compared to plain general anaesthesia (GA) group. Total amount of propofol required intraoperatively was less in CEGA group than in GA group. Recovery score and pain score (VAS) score were also compared which were better in CEGA group than in GA group. There were no significant intraoperative and postoperative complications noted in both the groups. Conclusion: Authors concluded that the use of epidural along with general anaesthesia helps in attenuating hemodynamic changes due to stress response to pneumoperitoneum, which results in maintaining stable intraoperative and postoperative hemodynamics during laparoscopic cholecystectomy surgery. Combining epidural to general anaesthesia results in rapid recovery as compared to plain general anaesthesia and also helps in providing good postoperative analgesia.
机译：背景：本研究的目的是比较GA硬膜外麻醉（CEGA）与单纯GA联合使用在减弱血液动力学反应和围手术期镇痛方面的功效。方法：作者进行了一项前瞻性，随机，双盲研究，其中60例患者接受了腹腔镜胆囊切除术。 A组（n = 30）接受GA，B组（n = 30）接受GA和硬膜外麻醉（CEGA）。作者分析了在血液动力学参数（心率，收缩压和舒张压），术中麻醉需要量（术中丙泊酚需要量），恢复评分和术后麻醉（VAS评分）方面，硬膜外联合全身麻醉与普通全身麻醉相比的效果。 。结果：作者发现硬膜外全麻（CEGA）组与普通全麻（GA）组相比，对气腹对应激反应的心率，收缩压和舒张压显着降低。 CEGA组术中所需的异丙酚总量少于GA组。比较CEGA组的恢复评分和疼痛评分（VAS）评分，GA组优于CEGA组。两组均未发现明显的术中和术后并发症。结论：作者得出的结论是，硬膜外麻醉和全身麻醉的使用有助于减轻由于对气腹产生的压力反应而引起的血液动力学变化，从而在腹腔镜胆囊切除术期间维持稳定的术中和术后血流动力学。与普通全身麻醉相比，硬膜外麻醉与全身麻醉相结合可快速恢复，并有助于提供良好的术后镇痛效果。

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