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首页> 外文期刊>International Journal of Research in Medical Sciences >Evaluate the differences in serum magnesium levels and lipid profile with correlation of hemoglobin A1C levels in type 2 diabetes patients: a case control study
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Evaluate the differences in serum magnesium levels and lipid profile with correlation of hemoglobin A1C levels in type 2 diabetes patients: a case control study

机译：评估2型糖尿病患者血清镁水平和血脂谱与血红蛋白A1C水平相关性的差异：病例对照研究

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Background: Magnesium deficiency is a common problem in diabetic patients. Magnesium deficiency may increase the incidence of Type 2 Diabetic (T2D) and occurrence complications. Objective of this study aimed at determining the differences in serum magnesium levels and lipid profile among patients newly diagnosed with T2D and normoglycemic individuals. Methods: The cross sectional observation study design was conducted at Sri Aurobindo Medical College, from March 2018 to April 2019. Source populations were all patients who attending to the OPD, Department of General Medicine. A total of 75 patients were enrolled in this study. This study was divided in two group’s cases group (T2D) and second control group (Non-diabetic). First group not initiated on any oral-hypoglycaemic, anti-hypertensive or lipid lowering drugs, and healthy patients were included in control group. Results: Triglycerides (TG), Total Cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C) showed significantly (p0.001) higher mean levels in T2D compared to the controls. The Magnesium and High-Density Lipoproteins-cholesterol (HDL-C) levels were significantly (p0.001) lower among the T2D group compared to the control group. There was a significant inverse correlation (r2= 0.567, p0.001) between Hemoglobin A1C (HbA1c) levels and serum magnesium. Conclusions: Serum magnesium levels and lipid profile were significantly different in T2D patients compared to control group.
机译：背景：镁缺乏症是糖尿病患者的常见问题。镁缺乏可能会增加2型糖尿病（T2D）的发生率和并发症的发生。这项研究的目的是确定新诊断为T2D和血糖正常的患者的血清镁水平和血脂谱的差异。方法：从2018年3月至2019年4月在Sri Aurobindo医学院进行横断面观察研究设计。来源人群均为参加普通科OPD的患者。共有75位患者参加了这项研究。这项研究分为两组：病例组（T2D）和第二对照组（非糖尿病）。第一组未开始使用任何口服降血糖药，抗高血压药或降脂药，而健康患者纳入对照组。结果：与对照组相比，甘油三酯（TG），总胆固醇（TC），低密度脂蛋白胆固醇（LDL-C）的T2D平均水平显着提高（p <0.001）。与对照组相比，T2D组中的镁和高密度脂蛋白胆固醇（HDL-C）水平显着降低（p <0.001）。血红蛋白A1C（HbA1c）水平与血清​​镁之间存在显着的负相关（r2 = 0.567，p <0.001）。结论：与对照组相比，T2D患者的血清镁水平和血脂水平显着不同。

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