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首页> 外文期刊>International Journal of Research in Medical Sciences >The diagnostic accuracy of fine needle aspiration cytology in leprosy: a clinico-histopathological correlation
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The diagnostic accuracy of fine needle aspiration cytology in leprosy: a clinico-histopathological correlation

机译：麻风细针穿刺细胞学检查的诊断准确性：临床组织病理学相关性

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Background: Leprosy is a chronic granulomatous condition mainly affects cooler parts of the body; skin, upper respiratory tract, anterior segment of the eye, superficial portion of peripheral nerves and testes. Redley and Joplin have classified it into five types; Tuberculoid (TT), Borderline Tuberculoid (BT), Mid Borderline (BB), Lepromatous Borderlilne (BL) and Lepromatous (LL). FNAC is simple, rapid and cost effective method over the biopsy to diagnose, classify and monitor leprosy in a patient. The present study was undertaken to evaluate and compare FNAC smears findings with histopathological findings and to classify lesions on RJ scale. Methods: This prospective and descriptive study was done in department of pathology in Sri Venkateshwara institute of medical science, pondicherry, India between June 2007 to June 2010. The patients were examined by the investigator with dermatologist later on slit smear was done. FNAC perform and comparison with biopsy and clinical history was done using SPSS software version 16.0. Results: Total 82 cases were included with age from 8 years to 79 years with mean age 38.16. Male to female ratio was 1.0: 0.7. FNAC shows parity 71.42% for tuberculoid and 58.33% for lepromatous leprosy and histopathology shows parity 100% for tuberculoid and 75% for lepromatous leprosy that indicate FNAC is useful usually for polar or stable group than the unstable or borderline cases. Conclusion: FNAC is a quick and safe for early diagnosis and classify cases into paucibacilary and multibacillary. Exact RJ Scale categorization on FNAC should not be used in isolation but FNAC should be supplemented to the histopathological diagnosis.
机译：背景：麻风病是一种慢性肉芽肿病，主要影响身体较凉的部位。皮肤，上呼吸道，眼前段，周围神经和睾丸的浅表部分。雷德利和乔普林将其分为五类。结核（TT），边界线（BT），中界线（BB），麻风性边界li（BL）和麻风性（LL）。与活检相比，FNAC是一种简单，快速且经济高效的方法，可用于诊断，分类和监测患者的麻风病。本研究旨在评估和比较FNAC涂片发现与组织病理学发现，并以RJ量表对病变进行分类。方法：这项前瞻性和描述性研究是在2007年6月至2010年6月间，在印度普奇里里的Sri Venkateshwara医学科学研究所的病理学部门进行的。研究人员随后与皮肤科医生共同对患者进行了裂隙涂片检查。使用SPSS软件16.0版完成FNAC的执行，并与活检和临床病史进行比较。结果：共纳入82例，年龄8〜79岁，平均38.16岁。男女比例为1.0：0.7。 FNAC显示结核病的奇偶性为71.42％，麻风性麻风病的奇偶性为58.33％，组织病理学显示结核病的奇偶性为100％，麻风病性麻风的奇偶性，这表明FNAC通常比不稳定或临界病例对极性或稳定人群有用。结论：FNAC是一种快速，安全的早期诊断方法，可将病例分类为脓杆菌和多杆菌。不应单独使用FNAC的确切RJ量表分类，而应将FNAC补充到组织病理学诊断中。

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