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首页> 外文期刊>International Journal of Research in Medical Sciences >Spectrum of pediatric urinary stone composition in North Western India: analysis at tertiary care center
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Spectrum of pediatric urinary stone composition in North Western India: analysis at tertiary care center

机译：印度西北部小儿泌尿系结石的频谱：三级护理中心的分析

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Background: Pediatric urolithiasis results in significant morbidity in later life. Incidence as well as site and chemical composition of calculi varies according to the changes in socio-economic conditions over time and the subsequent changes in dietary habits leading to a marked variation in the spectrum of urinary stone composition. To evaluate the spectrum of urinary stone composition in pediatric population from North-western India. Methods: This was a prospective observational study conducted between October 2013 and February 2019 which included pediatric patients with urolithiasis. Demographic and epidemiological characteristics including age, sex, geography, religion, socio-economic status, dietary habits were recorded. The location and sizes of stones were documented. The data was collected, analyzed and presented using summary statistics. Results: A total of 163 patients with urolithiasis were enrolled, of which 86 (53%) aged between 6 and 10 years, 49 (30%) aged between 11 and 14 years and 28 (17%) were aged between 0 and 5 years. The majority of patients were male (n=134; 82.21%). The most common location of the stone was urinary bladder (n=106; 65.03%) followed by kidney (n=33; 20.25%), urethra (n=16; 9.82%) and ureter (n=8; 4.91%). The upper tract (kidney and ureter) to the lower tract (bladder and urethra) stone ratio was 1:4. Stones with mixed composition were more than pure stones (73.62% versus 26.38%). The most common composition was the mixed stone of calcium oxalate, calcium phosphate and uric acid (n=36; 22.09%) followed by mixed stone of calcium oxalate monohydrate and dihydrate with uric acid (n=29; 17.79%), calcium oxalate and uric acid (n=25, 15.34%), calcium oxalate and calcium phosphate (n=20; 12.27%). Calcium oxalate was present in 80% of the stones, followed by uric acid in 7%, struvite in 6%, cystine in 3% and calcium phosphate in 2%. Conclusions: These results suggest that the prevalence of mixed stones with calcium oxalate as the predominant chemical component in the urinary stones of pediatric patients studied.
机译：背景：小儿尿路结石症在以后的生活中会导致大量发病。结石的发病率，部位和化学成分会随着社会经济状况随时间的变化以及随后饮食习惯的变化而发生变化，从而导致尿结石成分的光谱发生明显变化。为了评估印度西北部小儿人群尿结石成分的光谱。方法：这是一项于2013年10月至2019年2月之间进行的前瞻性观察性研究，纳入了患有尿路结石症的小儿患者。记录了人口统计和流行病学特征，包括年龄，性别，地理，宗教，社会经济地位，饮食习惯。记录了石头的位置和大小。使用汇总统计数据收集，分析和显示数据。结果：总共招募了163名尿路结石患者，其中86名（53％）年龄在6至10岁之间，49名（30％）年龄在11至14岁之间，28名（17％）年龄在0至5岁之间。大多数患者为男性（n = 134; 82.21％）。结石最常见的位置是膀胱（n = 106; 65.03％），其次是肾脏（n = 33; 20.25％），尿道（n = 16; 9.82％）和输尿管（n = 8; 4.91％）。上段（肾脏和输尿管）与下段（膀胱和尿道）的结石比率为1：4。具有混合成分的石头要比纯石头多（73.62％比26.38％）。最常见的成分是草酸钙，磷酸钙和尿酸的混合石（n = 36; 22.09％），其次是草酸钙一水合物和二水合物与尿酸的混合石（n = 29; 17.79％），草酸钙和尿酸（n = 25，15.34％），草酸钙和磷酸钙（n = 20; 12.27％）。草酸钙存在于80％的结石中，其次是尿酸（7％），鸟粪石（6％），胱氨酸（3％）和磷酸钙（2％）。结论：这些结果表明，以草酸钙为主要化学成分的混合性结石在小儿患者尿结石中的患病率较高。

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