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首页> 外文期刊>International journal of rheumatology >Asymptomatic Atherosclerosis in Egyptian Rheumatoid Arthritis Patients and Its Relation to Disease Activity
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Asymptomatic Atherosclerosis in Egyptian Rheumatoid Arthritis Patients and Its Relation to Disease Activity

机译：埃及类风湿关节炎患者无症状性动脉粥样硬化及其与疾病活动的关系

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Aim. To detect the frequency of subclinical atherosclerosis in rheumatoid arthritis patients without clinically evident atherosclerosis and to correlate its presence with the disease activity.Patients and Methods. Our study includes 112 RA patients (group 1) and 40 healthy controls (group 11). All patients and controls were subjected to full history taking, clinical examination, and laboratory investigations. Carotid intima media wall thickness (IMT) and carotid plaques were measured in both groups by B-mode ultrasonography; also color duplex Doppler ultrasound of the brachial artery was done to detect endothelial function.Results. There is atherosclerosis in 31.3% of asymptomatic RA patients compared with only 5% in controlsP=0.003**. A significant difference was detected in patients with and without atherosclerosis regarding duration of the diseaseP=0.0001***and patient’s ageP=0.01*. There is highly statistical significant correlation between atherosclerosis and disease activity index.Conclusion. The frequency of subclinical atherosclerosis was high in long-term active RA patients.
机译：目标。在没有临床上明显的动脉粥样硬化的类风湿关节炎患者中检测亚临床动脉粥样硬化的发生率，并将其存在与疾病活动相关联。我们的研究包括112名RA患者（第1组）和40名健康对照（第11组）。所有患者和对照均接受了完整的病史记录，临床检查和实验室检查。两组均行B超检查，测量颈动脉内膜中层厚度（IMT）和颈动脉斑块。还对肱动脉进行了彩色多普勒超声检查以检测内皮功能。无症状RA患者中有31.3％患有动脉粥样硬化，而对照组中只有5％（P = 0.003 **）。在患有和不患有动脉粥样硬化的患者中，疾病持续时间P = 0.0001 ***和患者年龄P = 0.01 *有显着差异。动脉粥样硬化与疾病活动指数之间存在极高的统计显着相关性。长期活跃的RA患者中亚临床动脉粥样硬化的发生率较高。

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