Characterization of the paclitaxel loaded chitosan graft Pluronic F127 copolymer micelles conjugate with a DNA aptamer targeting HER-2 overexpressing breast cancer cells

Kim Thach Nguyen; Thu Ha Nguyen; Dinh Ho Do; Quang Huan Le

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Characterization of the paclitaxel loaded chitosan graft Pluronic F127 copolymer micelles conjugate with a DNA aptamer targeting HER-2 overexpressing breast cancer cells

机译：紫杉醇负载的壳聚糖接枝Pluronic F127共聚物胶束与靶向HER-2过表达的乳腺癌细胞的DNA适体的表征

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In this work we report the isolation of DNA aptamer that is specifically bound to a HER-2 overexpressing SK-BR-3 human breast cancer cell line, using SELEX strategy. Paclitaxel (PTX) loaded chitosan graft Pluronic F127 copolymer micelles conjugate with a

机译：在这项工作中，我们报告了使用SELEX策略分离与HER-2过表达的SK-BR-3人乳腺癌细胞系特异性结合的DNA适体。紫杉醇（PTX）负载的壳聚糖接枝Pluronic F127共聚物胶束与

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《Advances in Natural Sciences: Nanoscience and Nanotechnology》 |2017年第1期|共9页
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Kim Thach Nguyen; Thu Ha Nguyen; Dinh Ho Do; Quang Huan Le;
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1. Development of chitosan graft pluronic?F127 copolymer nanoparticles containing DNA aptamer for paclitaxel delivery to treat breast cancer cells - IOPscience [J] . Kim Thach Nguyen, Duc Vinh Le, Dinh Ho Do, Advances in Natural Sciences: Nanoscience and Nanotechnology . 2016,第2期

机译：含DNA适体的壳聚糖接枝普能尼克®F127共聚物纳米颗粒用于紫杉醇递送治疗乳腺癌细胞的研究-IOPscience
2. Enhanced antitumor efficacy by paclitaxel-loaded pluronic P123/F127 mixed micelles against non-small cell lung cancer based on passive tumor targeting and modulation of drug resistance. [J] . Zhang W, Shi Y, Chen Y, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2010,第3期

机译：装载紫杉醇的普鲁尼克P123 / F127混合胶束可基于被动肿瘤靶向和耐药性调节增强对非小细胞肺癌的抗肿瘤功效。
3. Targeting Therapy of Neuropilin-1 Receptors Overexpressed Breast Cancer by Paclitaxel-Loaded CK3-Conjugated Polymeric Micelles [J] . Wang YaLi, Zhao Hang, Peng JinRong, Journal of biomedical nanotechnology . 2016,第12期

机译：紫杉醇负载的CK3共轭聚合物胶束对Neuropilin-1受体过表达乳腺癌的靶向治疗。
4. Paclitaxel-Loaded Micelles Modified with MCF-7 Cell-Specific Phage Protein: Enhance Selective Binding to Target Cancer Cells and Increased Cytotoxicity [C] . Tao Wang, Avni Clerk, Valery A Petrenko, Annual meeting exposition of the Controlled Release Society . 2010

机译：载有紫杉醇的胶束用MCF-7细胞特异性噬菌体蛋白修饰：增强对靶癌细胞的选择性结合并增加细胞毒性
5. Design and Evaluation of Peptidomimetics and Peptidomimetics Drug Conjugates Targeting HER2 Overexpressing Cells in Breast and Lung Cancers [D] . Pallerla, Sandeep. 2017

机译：拟肽和拟肽药物结合物靶向乳腺癌和肺癌中HER2过表达细胞的设计和评估
6. Bufalin-loaded vitamin E succinate-grafted-chitosan oligosaccharide/RGD conjugated TPGS mixed micelles demonstrated improved antitumor activity against drug-resistant colon cancer [O] . Zeting Yuan, Yuxia Yuan, Lin Han, 2018

机译：载有Bufalin的维生素E琥珀酸酯接枝的壳聚糖寡糖/ RGD共轭的TPGS混合胶束表现出对耐药性结肠癌的改善的抗肿瘤活性
7. Bufalin-loaded vitamin E succinate-grafted-chitosan oligosaccharide/RGD conjugated TPGS mixed micelles demonstrated improved antitumor activity against drug-resistant colon cancer [O] . Zeting Yuan, Yuxia Yuan, Lin Han, 2018

机译：加载Bufalin加载的维生素E琥珀酸壳壳聚糖寡糖/ RGD共轭TPGS混合胶束显示出改善抗耐药性结肠癌的抗肿瘤活性
8. Targeting Human Breast Cancer Cells that Overexpress HER-2/neu mRNA by an Antisense Iron Responsive Element [R] . Yan, D. 2003

机译：靶向通过反义铁响应元件过表达HER-2 / neu mRNa的人乳腺癌细胞

Characterization of the paclitaxel loaded chitosan graft Pluronic F127 copolymer micelles conjugate with a DNA aptamer targeting HER-2 overexpressing breast cancer cells

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