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首页> 外文期刊>International Journal of TROPICAL DISEASE & Health >Active Case Detection and Prevalence of Urinary Schistosomiasis and Malaria in Pupils of Kotto Barombi, Southwest Cameroon Using the CyScope? Fluorescence Microscope
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Active Case Detection and Prevalence of Urinary Schistosomiasis and Malaria in Pupils of Kotto Barombi, Southwest Cameroon Using the CyScope? Fluorescence Microscope

机译：使用CyScope在喀麦隆西南部Kotto Barombi的学生中主动检测病例和尿血吸虫病和疟疾的流行？荧光显微镜

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Aim: This study was aimed at assessing the use of the CyScope? fluorescence microscope to determine the prevalence of urinary schistosomiasis (US) and malaria in Kotto Barombi. Experimental Design: The study was a cross-sectional survey. Place and Duration of Study: The study was carried out in Kotto Barombi, Cameroon from April to May, 2013. Methodology: Urine and blood samples were collected from 216 pupils. US eggs were detected in urine by centrifugation and CyScope? methods for schistosome eggs. Malaria parasites were detected using Giemsa-stained blood films and CyScope? methods. The performance characteristics of the CyScope? for both infections were determined using light microscopy as gold standard. Results: Overall prevalence of US was 43.4% and 48.5% by light microscopy and CyScope? respectively. Prevalence of US was significantly higher ( P <0.01) in the Kotto Barombi Island (78.3%) than Mainland (33.8%). US prevalence was not affected by age, sex and socio-economic class (SEC). Mean intensity of US was 8.1 eggs/10 ml urine (Confidence interval, CI = 4.3–11.9). It was significantly higher (P =.01) in pupils from Island (36.5 eggs/10 ml, CI: 17.7–55.3) than Mainland (8.8 eggs/10 ml; 7.1–10.5), males (19.2 eggs/10 ml urine; CI: 9.2–29.2) than females (17.8 eggs/10 ml urine; CI: 13.1–22.5) and highest ( P = .046) in the ≤6 years age group (36.9 eggs/10 ml; CI: 20.4–53.4) when compared with pupils in other age groups. Sensitivity and specificity of CyScope? for US were 90.6% and 83.8% respectively. Overall prevalence of malaria was 19.0% and 41.2% by light microscopy and CyScope? respectively and the difference was significant ( P = .01). Malaria prevalence and density were not influenced by age; sex and SEC. Sensitivity and specificity of CyScope? for malaria were 68.3% and 64.9% respectively. Conclusion: The CyScope? could be a useful tool for active case detection of both diseases especially in areas that lack electricity.
机译：目的：本研究旨在评估CyScope的使用？荧光显微镜可确定科托巴隆比市的尿血吸虫病（美国）和疟疾患病率。实验设计：该研究为横断面调查。研究的地点和时间：该研究于2013年4月至5月在喀麦隆的Kotto Barombi进行。方法：从216名学生那里收集了尿液和血液样本。通过离心和CyScope检测尿液中的US卵？血吸虫卵的方法。使用吉姆萨染色的血膜和CyScope？检测疟原虫。方法。 CyScope的性能特点？使用光学显微镜作为金标准确定两种感染的感染率。结果：通过光学显微镜和CyScope，美国的总体患病率为43.4％和48.5％。分别。在科托巴隆比岛（78.3％），美国的患病率显着高于大陆（33.8％）（P <0.01）。美国的患病率不受年龄，性别和社会经济阶层（SEC）的影响。 US的平均强度为8.1卵/ 10 ml尿液（置信区间，CI = 4.3–11.9）。海岛（36.5个鸡蛋/ 10毫升，CI：17.7-55.3）的学生显着高于大陆（8.8个鸡蛋/ 10毫升; 7.1-10.5），男生（19.2个鸡蛋/ 10毫升尿液; P = .01）。 CI：9.2–29.2）比女性（17.8个鸡蛋/ 10 ml尿; CI：13.2–22.5）和≤6岁年龄组最高（P = .046）（36.9个鸡蛋/ 10 ml; CI：20.4–53.4）与其他年龄段的学生相比CyScope的敏感性和特异性？美国分别为90.6％和83.8％。光学显微镜和CyScope检测显示，疟疾的总体患病率分别为19.0％和41.2％。且差异显着（P = 0.01）。疟疾的流行和密度不受年龄的影响;性和SEC。 CyScope的敏感性和特异性？疟疾的比例分别为68.3％和64.9％。结论：CyScope？可以作为主动检测两种疾病的有用工具，尤其是在缺电地区。

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