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首页> 外文期刊>International Journal of Pharmacy and Pharmaceutical Sciences >PATTERNS OF PRESCRIPTION AND ANTIBIOTIC USE AMONG OUTPATIENTS IN A TERTIARY CARE TEACHING HOSPITAL OF BANGLADESH
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PATTERNS OF PRESCRIPTION AND ANTIBIOTIC USE AMONG OUTPATIENTS IN A TERTIARY CARE TEACHING HOSPITAL OF BANGLADESH

机译：孟加拉国三级医疗教学医院门诊患者的处方和抗生素使用方式

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Objective : Irrational drug use increased the risk of adverse drug reactions (ADRs), the emergence of drug resistance and a leading cause of morbidity and mortality worldwide. The study was designed to analyse prescription patterns and antibiotic use among outpatients in a tertiary care teaching hospital in Bangladesh. Methods: This prospective survey was conducted among the out-patients in a district hospital. The prescribed drugs were classified according to Anatomical and Therapeutic Chemical (ATC) classification system. Patient characteristics and drug data were recorded. The prescription pattern was analysed using general drug use indicators according to world health organisation (WHO). Results: A total of 405 prescriptions were analyzed of which 54% of child and 46% of adult prescriptions. The age and body weight of the patients were not mentioned in 30% of child and 62% of adult prescriptions and none of the prescriptions included sex of the patients. Physician’s handwriting was not clear and legible in 31% prescriptions. A total 1362 drugs were used in this study with an average 3.36 drugs per prescription. However, none of the drugs was prescribed in generic name. Children were highly exposed to antibiotics (66%) than to adults (44%) of which cephalosporin’s (30%) and macrolides (14%) were commonly used. Interestingly, non-steroidal anti-inflammatory drugs (NSAIDs) were also highly accounted in children (53%) than to adults (36%). Conclusion: Our results suggested that the prescription information was incomplete and physicians did not follow the standard guideline for drug treatment resulting in polypharmacy and indiscriminate use of antimicrobials irrespective to the age of patients.
机译：目的：不合理地使用毒品会增加全球药物不良反应（ADR）的风险，耐药性的出现以及发病率和死亡率的主要原因。该研究旨在分析孟加拉国一家三级护理教学医院门诊患者的处方模式和抗生素使用情况。方法：这项前瞻性调查是在地区医院的门诊病人中进行的。处方药根据解剖和治疗化学（ATC）分类系统分类。记录患者特征和药物数据。根据世界卫生组织（WHO）使用一般药物使用指标对处方模式进行了分析。结果：共分析了405张处方，其中54％的儿童处方药和46％的成人处方药。在30％的儿童和62％的成人处方中未提及患者的年龄和体重，并且这些处方均未包含患者的性别。在31％的处方中，医师的笔迹不清楚且清晰可辨。这项研究总共使用了1362种药物，每个处方平均使用3.36种药物。但是，这些药物均未以通用名称开处方。儿童比成年人（44％）接触抗生素的比例更高（66％），其中通常使用头孢菌素（30％）和大环内酯类（14％）。有趣的是，非甾体类抗炎药（NSAIDs）在儿童（53％）中也占成年人（36％）的比例很高。结论：我们的结果表明处方信息不完整，医生没有遵循药物治疗的标准指南，从而导致多药店和不分年龄的患者而滥用抗生素。

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