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首页> 外文期刊>Intestinal research. >The Clinical Usefulness of Endoscopic Ultrasound-Guided Fine Needle Aspiration and Biopsy for Rectal and Perirectal Lesions
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The Clinical Usefulness of Endoscopic Ultrasound-Guided Fine Needle Aspiration and Biopsy for Rectal and Perirectal Lesions

机译:内镜超声引导下细针穿刺活检对直肠和直肠周围病变的临床价值

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Background/Aims Endoscopic ultrasound-guided fine needle aspiration and/or biopsy (EUS-FNA/B) have been used to diagnose subepithelial tumors (SETs) and extraluminal lesions in the gastrointestinal tract. Our group previously reported the usefulness of EUS-FNA/B for rectal and perirectal lesions. This study reports our expanded experience with EUS-FNA/B for rectal and perirectal lesions in terms of diagnostic accuracy and safety. We also included our new experience with EUS-FNB using the recently introduced ProCore needle. Methods From April 2009 to March 2014, EUS-FNA/B for rectal and perirectal lesions was performed in 30 consecutive patients. We evaluated EUS-FNA/B performance by comparing histological diagnoses with final results. We also investigated factors affecting diagnostic accuracy. Results Among 10 patients with SETs, EUS-FNA/B specimen results revealed a gastrointestinal stromal tumor in 4 patients and malignant lymphoma in 1 patient. The diagnostic accuracy of EUS-FNA/B was 50% for SETs (5/10). Among 20 patients with non-SET lesions, 8 patients were diagnosed with malignant disease and 7 were diagnosed with benign disease based on both EUS-FNA/B and the final results. The diagnostic accuracy of EUS-FNA/B for non-SET lesions was 75% (15/20). The size of lesions was the only factor related to diagnostic accuracy ( P =0.027). Two complications of mild fever and asymptomatic pneumoperitoneum occurred after EUS-FNA/B. Conclusions The overall diagnostic accuracy of EUS-FNA/B for rectal and perirectal lesions was 67% (20/30). EUS-FNA/B is a clinically useful method for cytological and histological diagnoses of rectal and perirectal lesions.
机译:背景/目的内镜超声引导下细针穿刺活检和/或活检(EUS-FNA / B)已被用于诊断胃肠道上皮下肿瘤(SET)和腔外病变。我们的小组先前曾报道EUS-FNA / B对于直肠和直肠周围病变的有用性。这项研究报告了我们在诊断准确性和安全性方面对直肠和直肠周围病变使用EUS-FNA / B的丰富经验。我们还介绍了使用最近推出的ProCore针头进行EUS-FNB的新经验。方法2009年4月至2014年3月,对连续30例患者行直肠和直肠周围病变EUS-FNA / B检查。我们通过比较组织学诊断结果和最终结果来评估EUS-FNA / B的表现。我们还调查了影响诊断准确性的因素。结果10例SET患者中,EUS-FNA / B标本检查结果显示4例患者患有胃肠道间质瘤,其中1例患者发现恶性淋巴瘤。对于SET(5/10),EUS-FNA / B的诊断准确性为50%。根据EUS-FNA / B和最终结果,在20例非SET病变的患者中,有8例被诊断为恶性疾病,有7例被诊断为良性疾病。 EUS-FNA / B对非SET病变的诊断准确性为75%(15/20)。病变的大小是与诊断准确性有关的唯一因素(P = 0.027)。 EUS-FNA / B后发生轻度发烧和无症状气腹两种并发症。结论EUS-FNA / B对直肠和直肠周围病变的总体诊断准确性为67%(20/30)。 EUS-FNA / B是对直肠和直肠周围病变进行细胞学和组织学诊断的临床有用方法。

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