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首页> 外文期刊>Intestinal research. >Comparison of the efficacy of disinfectants in automated endoscope reprocessors for colonoscopes: tertiary amine compound (Sencron2?) versus ortho-phthalaldehyde (Cidex?OPA)
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Comparison of the efficacy of disinfectants in automated endoscope reprocessors for colonoscopes: tertiary amine compound (Sencron2?) versus ortho-phthalaldehyde (Cidex?OPA)

机译：结肠镜自动内窥镜清洗机中消毒剂功效的比较：叔胺化合物（Sencron2？）与邻苯二甲醛（Cidex®OPA）

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Background/Aims To prevent the transmission of pathogens by endoscopes, following established reprocessing guidelines is critical. An ideal reprocessing step is simple, fast, and inexpensive. Here, we evaluated and compared the efficacy and safety of two disinfectants, a tertiary amine compound (TAC) and ortho-phthalaldehyde (OPA). Methods A total of 100 colonoscopes were randomly reprocessed using two same automated endoscope reprocessors, according to disinfectant. The exposure time was 10 minutes for 0.55% OPA (Cidex? OPA, Johnson & Johnson) and 5 minutes for 4% TAC (Sencron2?, Bab Gencel Pharma & Chemical Ind. Co.). Three culture samples were obtained from each colonoscope after reprocessing. Results A total of nine samples were positive among the 300 culture samples. The positive culture rate was not statistically different between the two groups (4% for OPA and 2% for TAC, P =0.501). There were no incidents related to safety during the study period. Conclusions TAC was non-inferior in terms of reprocessing efficacy to OPA and was safe to use. Therefore, TAC seems to be a good alternative disinfectant with a relatively short exposure time and is also less expensive than OPA.
机译：背景/目的为了防止内窥镜传播病原体，遵循既定的后处理准则至关重要。理想的后处理步骤是简单，快速且廉价的。在这里，我们评估并比较了两种消毒剂叔胺化合物（TAC）和邻苯二甲醛（OPA）的功效和安全性。方法根据消毒剂，使用两个相同的自动内窥镜洗消机对100台结肠镜进行了随机处理。对于0.55％的OPA（CidexOPA，强生公司），暴露时间为10分钟，对于4％的TAC（Sencron2，Bab Gencel Pharma＆Chemical Ind.Co.）为5分钟。重新处理后，从每个结肠镜获得三个培养物样品。结果300份培养样品中总共有9份阳性。两组之间的阳性培养率无统计学差异（OPA为4％，TAC为2％，P = 0.501）。在研究期间没有安全相关的事件。结论TAC在后处理功效方面不亚于OPA，并且使用安全。因此，TAC似乎是一种很好的替代消毒剂，具有相对较短的暴露时间，并且比OPA便宜。

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