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首页> 外文期刊>International Journal of Surgical Oncology >No Excess Mortality in Patients Aged 50 Years and Older Who Received Treatment for Ductal CarcinomaIn Situof the Breast
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No Excess Mortality in Patients Aged 50 Years and Older Who Received Treatment for Ductal CarcinomaIn Situof the Breast

机译：接受乳腺导管癌治疗的50岁及50岁以上患者的死亡率没有过多

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Background. The incidence of ductal carcinomain situ(DCIS) has increased at a fast rate.The aim of this study was to assess the incidence and treatment in the Netherlands and estimate the excess mortality risk of DCIS.Methods. From the Netherlands Cancer Registry, adult female patients (diagnosed 1997–2005) with DCIS were selected. Treatment was described according to age. Relative mortality at 10 years of follow-up was calculated by dividing observed mortality over expected mortality. Expected mortality was calculated using the matched Dutch general population.Results. Overall, 8421 patients were included in this study. For patients aged 50–64, and 65–74 an increase in breast-conserving surgery was observed over time (P<0.001). For patients over 75 years of age, 8.0% did not undergo surgery; this percentage remained stable over time (P=0.07). Overall, treated patients aged >50 years experienced no excess mortality regardless of treatment (relative mortality 1.0).Conclusion. The present population-based study of almost 8500 patients showed no excess mortality in surgically treated women over 50 years with DCIS.
机译：背景。导管原位癌（DCIS）的发生率迅速增加。本研究的目的是评估荷兰的发生率和治疗方法，并估计DCIS的额外死亡风险。从荷兰癌症登记处选择DCIS成年女性患者（诊断为1997-2005年）。根据年龄描述了治疗方法。通过将观察到的死亡率除以预期死亡率来计算10年随访期的相对死亡率。使用匹配的荷兰总人口计算出预期死亡率。总体而言，这项研究包括了8421名患者。对于50-64岁和65-74岁的患者，随着时间的推移，观察到的保乳手术有所增加（P <0.001）。对于75岁以上的患者，8.0％的人没有接受手术;该百分比随时间保持稳定（P = 0.07）。总体而言，年龄大于50岁的接受治疗的患者无论接受何种治疗均无过度死亡率（相对死亡率1.0）。结论。目前基于人群的研究对近8500名患者进行了研究，结果显示，经DCIS手术治疗的女性在50年以上的死亡率没有增加。

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