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首页> 外文期刊>Iranian journal of clinical infectious diseases >Ecthyma gangrenosum Due to Escherichia coli Bacteremia in a Patient with Acute Myeloid Leukemia: A Case Report and a Literature Review About E. coli-Induced Ecthyma gangrenosum
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Ecthyma gangrenosum Due to Escherichia coli Bacteremia in a Patient with Acute Myeloid Leukemia: A Case Report and a Literature Review About E. coli-Induced Ecthyma gangrenosum

机译：急性髓性白血病患者因大肠杆菌细菌血症而导致的坏疽性大肠埃希菌：1例病例报道和有关大肠杆菌诱导的坏疽性大肠埃希菌的文献综述

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Ecthyma gangrenosum is a skin lesion presenting invasive infection in the skin, which is commonly caused by Pseudomonas. Pathogenesis is mostly attributed to the microbial invasion in cutaneous tissues caused by the microorganism. One of the important, but rare causes of Ecthyma gangrenosum after Pseudomonas is Escherichia coli.A 45-year-old woman known as a case with acute myeloid leukemia who went into remission due to chemotherapy. After chemotherapy, she was febrile and septic. A physical examination revealed an erythematous round lesion (3 ?? 3 cm) that had developed on the posterior aspect of the right thigh with central bolus necrosis. E. coli was detected based on both blood cultures.Ecthyma gangrenosum is mostly seen in patients with severe immunodeficiency such as aplastic anemia, hematologic malignancies, especially patients with leukemia after chemotherapy and also in HIV patients. So far, in 11 patients reported in the literature, at least 8 cases are reported lesions on the lower limb, which is the most probable anatomic area for E. coli-induced Ecthyma gangrenosum. The E. coli-induced Ecthyma gangrenosum is a rare infectious lesion that is particularly seen in patients with a malignancy history, and lower extremity lesions should be considered.
机译：坏疽性皮囊炎是一种皮肤病变，表现为皮肤中的浸润性感染，通常由假单胞菌引起。发病机理主要归因于微生物在皮肤组织中引起的微生物入侵。假单胞菌引起的坏疽性大肠埃希氏菌的重要但罕见的原因之一是大肠杆菌。一名45岁的女性，因急性髓性白血病而闻名，因化疗而缓解。化疗后，她发热且脓毒症。体格检查发现右大腿后侧出现红斑圆形病变（3 ?? 3厘米），并出现中央团块坏死。两种血培养均检测到大肠杆菌。坏死性坏死多数见于严重的免疫缺陷患者，如再生障碍性贫血，血液系统恶性肿瘤，尤其是化疗后的白血病患者以及HIV患者。迄今为止，在文献中报道的11例患者中，至少有8例报告了下肢病变，这是大肠杆菌诱导的坏疽性大疱性大肠杆菌的最可能的解剖区域。大肠杆菌诱导的坏疽性皮炎是一种罕见的感染性病变，尤其在具有恶性病史的患者中尤为明显，应考虑下肢病变。

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