Medicinal Plants as Potential New Target Drugs in Endocrine Disorders- Review Article

Shirin HASANI-RANJBAR; Bagher LARIJANI

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Medicinal Plants as Potential New Target Drugs in Endocrine Disorders- Review Article

机译：药用植物作为内分泌失调的潜在新靶标药物-评论文章

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Noncommunicable diseases pose a real threat to and their incidence is forecast to increase in both developed and developing countries; and, diabetes, obesity, and related complications are predicted to pose a great burden on health care systems all across the world. However, current used conventional medications and surgical interventions fall short of effectively controlling the rampant spread of obesity and diabetes. Moreover, as the world population grows older, increases the need for more effectively controlling old-age diseases such as obesity and diabetes. It is clear that many traditional plants are used for treatment of diseases in Iran and throughout the world as adjuncts to conventional therapy. This work aimed to present current science on the efficacy and safety of medicinal plants useful in diabetes mellitus, obesity, hyperlipidemia, hyper prolacrinemia and antioxidant effects by reviewing all human and some animal studies. Amongst reviewed studies, some natural products were found effective in the treatment of these metabolic disorders that deserve further works to isolate and characterization of their constituents to reach novel therapeutic agents. The findings of the current study demonstrated that some medicinal plants are effective in the treatment of different metabolic and endocrine disorders. For example Citrulluscolocynthis, Silybummarianum, Psyllium, Teucriumpolium, pomegranate, ginseng, Aloe vera and fenugreek decreased blood glucose significantly. Moreover, a variety of herbal supplements were found to be effective in the management of obesity such as ephedra, cissusquadrangularis, ginseng, bitter melon (Momordicacharantia), and zingiber.

机译：非传染性疾病构成了真正的威胁，在发达国家和发展中国家，非传染性疾病的发病率都将增加;并且，糖尿病，肥胖症和相关并发症预计将给全世界的卫生保健系统带来巨大负担。然而，当前使用的常规药物和外科手术不能有效控制肥胖症和糖尿病的猖the蔓延。此外，随着世界人口的老龄化，对更有效地控制诸如肥胖症和糖尿病等老年疾病的需求也在增加。显然，许多传统植物被用作常规疗法的辅助手段，在伊朗和全世界用于治疗疾病。这项工作旨在通过回顾所有人类和一些动物研究来介绍可用于糖尿病，肥胖，高脂血症，高泌乳素血症和抗氧化作用的药用植物功效和安全性的当前科学。在已审查的研究中，发现一些天然产物可有效治疗这些代谢紊乱，值得进一步研究以分离和鉴定其成分，从而获得新型治疗剂。当前研究的结果表明，某些药用植物可有效治疗不同的代谢和内分泌疾病。例如，柑桔，水飞蓟，车前子，白头翁，石榴，人参，芦荟和胡芦巴明显降低了血糖。此外，发现多种草药补充剂可有效治疗肥胖症，如麻黄，顺式红参，人参，苦瓜（苦瓜）和姜。

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《Iranian journal of public health.》 |2014年第1期|共11页
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Shirin HASANI-RANJBAR; Bagher LARIJANI;
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1. Medicinal Plants as Potential New Target Drugs in Endocrine Disorders- Review Article [J] . Shirin HASANI-RANJBAR, Bagher LARIJANI Iranian journal of public health. . 2014,第1Suppla期

机译：药用植物作为内分泌疾病的潜在新靶标药物-评论文章
2. Recent Update on Animal and Human Evidences of Promising Antidiabetic Medicinal Plants: A Mini-review of Targeting New Drugs [J] . Shirin Hasani Ranjbar, Bagher Larijani, Mohammad Abdollahi Asian journal of animal and veterinary advances . 2011,第12期

机译：有前途的抗糖尿病药用植物的动物和人类证据的最新进展：针对新药的迷你审查。
3. Recent Update on Animal and Human Evidences of Promising Anti-diabetic Medicinal Plants: A Mini-review of Targeting New Drugs [J] . Shirin Hasani Ranjbar, Bagher Larijani, Mohammad Abdollahi Asian journal of animal and veterinary advances . 2011,第12期

机译：有希望的抗糖尿病药用植物的动物和人类证据的最新进展：针对新药的迷你审查。
4. Investigation of Therapeutic Potentials of Some Selected Medicinal Plants Using Neutron Activation Analysis [C] . Sani Abubakar, Ahmed Rufai Usman, Nasiru Fage Isa, National Physics Conference . 2015

机译：使用中子激活分析对一些选定药用植物治疗潜力的研究
5. Potential new sources of cardiovascular drugs from phylogenetic and pharmacological analyses of medicinally used plants [D] . Guzman, Emily. 2018

机译：从药用植物的系统发育和药理学分析中发现潜在的心血管药物新来源
6. A Comprehensive Review on Medicinal Plants as Antimicrobial Therapeutics: Potential Avenues of Biocompatible Drug Discovery [O] . Uttpal Anand, Nadia Jacobo-Herrera, Ammar Altemimi, 2019

机译：药用植物作为抗菌药物的全面审查：生物相容性药物发现的潜在途径。
7. ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices—Summary Article A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committee to Update the 1998 Pacemaker Guidelines) 11This document was approved by the American College of Cardiology Foundation Board of Trustees in September 2002, the American Heart Association Science Advisory and Coordinating Committee in August 2002, and the North American Society for Pacing and Electrophysiology in August 2002.22The ACC/AHA Task Force on Practice Guidelines makes every effort to avoid any actual or potential conflicts of interest that might arise as a result of an outside relationship or personal interest of a member of the writing panel. Specifically, all members of the writing panel are asked to provide disclosure statements of all such relationships that might be perceived as real or potential conflicts of interest. These statements are reviewed by the parent task force, reported orally to all members of the writing panel at the first meeting, and updated as changes occur. The conflict of interest information for the writing committee members is posted on the ACC, AHA, and NASPE Web sites with the full-length version of the update.33When citing this document, the ACC, the AHA, and NASPE would appreciate the following citation format: Gregoratos G, Abrams J, Epstein AE, Freedman RA, Hayes DL, Hlatky MA, Kerber RE, Naccarelli GV, Schoenfeld MH, Silka MJ, Winters SL. ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices—Summary Article: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committee to Update the 1998 Pacemaker Guidelines). J Am Coll Cardiol2002;40:1703–19.44Copies: This document is available on the World Wide Web sites of the ACC (www.acc.org) and the AHA (www.americanheart.org). A single copy of the complete guidelines is available by calling 800-253-4636 (US only) or writing the American College of Cardiology, Resource Center, 9111 Old Georgetown Road, Bethesda, MD 20814-1699 (ask for No. 71-0237). To obtain a copy of the Summary Article, ask for reprint No. 71-0236. To purchase additional reprints (specify version and reprint number): up to 999 copies, call 800-611-6083 (US only) or fax 413-665-2671; 1000 or more copies, call 410-528-4426, fax 410-528-4264, or e-mail kbradle@lww.com.55(J Am Coll Cardiol 2002;40:1703–19.)66©2002 by the American College of Cardiology Foundation and the American Heart Association, Inc. [O] . Gregoratos Gabriel, Abrams Jonathan, Epstein Andrew E, 2002

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Medicinal Plants as Potential New Target Drugs in Endocrine Disorders- Review Article

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