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首页> 外文期刊>Iranian journal of public health. >Prevalence of Cefepime-Resistant Escherichia coli in Iran: A Meta-Analysis (2007-2016)
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Prevalence of Cefepime-Resistant Escherichia coli in Iran: A Meta-Analysis (2007-2016)

机译:伊朗对头孢吡肟耐药的大流行:一项荟萃分析(2007-2016)

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Background: Cefepime-resistant Escherichia coli (E. coli) is one of the seven important types of microbial resistance. This meta-analysis study was conducted to identify the prevalence of cefepime-resistant E. coli in Iran during 2007-2016. Methods: Studies published were searched in Persian databases (including Magiran, and SID) and international databases (including PubMed, ScienceDirect, and Scopus). The selected studies included all types of laboratory methods. Moreover, the random effects model (DerSimonian Laird method) was used to addresses the high heterogeneity (50% I2) between the reviewed studies. The collected data were categorized into different subgroups on the basis of the year of study and province. Data analysis was performed using the Statsdirect software. Results: Overall, 516 articles were selected from the searched medical databases. After reviewing and applying the inclusion criteria, irrelevant papers were excluded and the remaining 26 studies were meta-analyzed. The overall prevalence of cefepime-resistant E. coli was 53.42% (95%: 43.35, 63.35), ranging from 25% (95%CI: 21.67, 28.55) in 2009 to 61.95% (95%CI: 56.62, 67.09) in 2016. Conclusion: The prevalence of cefepime-resistant E. coli in Iran has had an increasing and alarming trend during the recent years. Therefore, it is necessary to use practical strategies and interventions to control and monitor cefepime-resistant E. coli in the country.
机译:背景:头孢吡肟抗性大肠杆菌(E. coli)是七种重要的微生物抗性类型之一。这项荟萃分析研究旨在确定2007-2016年期间伊朗对头孢吡肟耐药的大肠杆菌的患病率。方法:在波斯数据库(包括Magiran和SID)和国际数据库(包括PubMed,ScienceDirect和Scopus)中搜索已发表的研究。选定的研究包括所有类型的实验室方法。此外,在回顾的研究之间,使用随机效应模型(DerSimonian Laird方法)来解决高异质性(50%

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