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Mesothelioma in Italy:the Casale Monferrato modelto a national epidemiologicalsurveillance system

机译:意大利间皮瘤:国家流行病学监测系统的Casale Monferrato模型

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The purpose of the present paper is to review the origin and development of the epidemiologyof mesothelioma in Italy, starting with the detection and investigation of the majoroutbreak of the disease observed in Casale Monferrato, Piedmont Region. Over the lastfour decades, mortality among the cohort of ex-Eternit workers has been measured atthree points in time. More recently, population based case-control studies in the area ofCasale Monferrato have provided new light on the dose-response curve of the relationshipbetween asbestos exposure and mesotheliomas. The publication of the first CasaleMonferrato study had a major impact in the country and contributed to the decision ofthe Italian Parliament to ban the use of asbestos. The experience of Casale Monferratorepresents a lesson in several terms, from the epidemiological surveillance to the healthcare of the victims and the relationship between epidemiologists, victims, their relativesand residents in contaminated areas.
机译:本文的目的是回顾和研究意大利间皮瘤流行病学的起源和发展,首先是对皮埃蒙特地区卡萨莱·蒙费拉托的主要疾病暴发进行检测和调查。在过去的四十年中,曾在三个时间点测量过前埃特里尼工人的死亡率。最近,Casale Monferrato地区基于人群的病例对照研究为石棉暴露与间皮瘤之间关系的剂量反应曲线提供了新的思路。 CasaleMonferrato的第一项研究报告的发表对该国产生了重大影响,并有助于意大利议会决定禁止使用石棉。从流行病学监测到受害者的医疗保健,以及流行病学家,受害者,他们的亲戚和受污染地区居民之间的关系,Casale Monferratore的经历从几个方面代表了一个教训。

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