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首页> 外文期刊>Eastern Mediterranean Health Journal: Al-Magallat al-Sihhiyyat li-Sarq al-Mutawassit >First report on Leishmania major/HIV coinfection in a Sudanese patient
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First report on Leishmania major/HIV coinfection in a Sudanese patient

机译：有关一名苏丹患者的大流行利什曼原虫/ HIV合并感染的首次报告

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Leishmania/HIV coinfection is a new clinical form of leishmaniasis that has been reported in more than 35 countries [1,2]. The World Health Organization (WHO) estimates that 39.5 million people are infected by HIV worldwide and that one-third of them live in Leishmania-endemic regions [1,2]. Most of the reported Leishmania/HIV coinfections were among patients infected with viscerotropic parasites, but few data are available on L. major/HIV coinfection [2]. Coinfection of HIV patients with Leishmania spp. can occur naturally through infected vectors or artificially among intravenous drug users and recipients of blood transfusion. The coinfection modulates the severity of the clinical presentation of leishmaniasis and interferes with proper diagnosis. Leishmania/HIV coinfection of patients can result in the emergence of diverse Leishmania parasite clones; suppresses the host immune response; and increases blood parasitaemia, hence enhancing transmission. The coinfection also reduces the response of patients to antileishmanial drugs [3].
机译：利什曼病/ HIV合并感染是利什曼病的一种新的临床形式，已在超过35个国家中报道[1,2]。世界卫生组织（WHO）估计，全世界有3950万人感染了艾滋病毒，其中三分之一居住在利什曼原虫流行地区[1,2]。大部分报道的利什曼原虫/ HIV合并感染都属于内吸性寄生虫感染的患者，但是关于大乳酸杆菌/ HIV合并感染的数据很少[2]。 HIV患者与利什曼原虫的共感染。可以通过感染的载体自然发生，也可以在静脉吸毒者和输血接受者中人工发生。合并感染调节利什曼病的临床表现的严重性并干扰正确的诊断。患者的利什曼原虫/ HIV合并感染可导致出现多种利什曼原虫寄生虫克隆。抑制宿主的免疫反应;并增加血液寄生虫血症，从而增强传播。共感染还降低了患者对抗衰老药物的反应[3]。

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