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首页> 外文期刊>Eastern Mediterranean Health Journal: Al-Magallat al-Sihhiyyat li-Sarq al-Mutawassit >Evaluation of factors associated with failure of tuberculosis treatment under DOTS in northern Islamic Republic of Iran
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Evaluation of factors associated with failure of tuberculosis treatment under DOTS in northern Islamic Republic of Iran

机译：伊朗北部伊斯兰共和国在DOTS下与结核病治疗失败相关的因素评估

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摘要

Tuberculosis treatment failure remains a major health problem in many parts of the Islamic Republic of Iran. This study was conducted to identify the risk factors associated with failure of tuberculosis treatment under the DOTS strategy in two cities of Golestan province. A retrospective cohort study in 2012–2013 was conducted on 167 smear-positive tuberculosis patients monitored under DOTS. Demographic, clinical and treatment outcome factors and social determinants of health were recorded for each patient. Multivariate regression analysis found that the strongest predictors of tuberculosis treatment failure were being infected with other diseases (OR 9.35; 95% CI 3.01–29.1), male sex (OR 5.03; 95% CI 1.58–16.1), Turkoman ethnicity (OR 11.0; 95% CI 2.00–60.1), family history of tuberculosis (OR 0.21; 95% CI 0.05–0.96) and household size (OR 1.21; 95% CI 0.99–1.48). Recommendations include better follow-up for patients with other diseases and facilitating access to treatment, especially for Turkoman patients.
机译：结核病治疗失败仍然是伊朗伊斯兰共和国许多地区的主要健康问题。这项研究的目的是确定在哥伦斯坦省的两个城市，在DOTS策略下与结核病治疗失败相关的危险因素。在2012-2013年期间对167例接受DOTS监测的涂片阳性结核病患者进行了回顾性队列研究。记录每位患者的人口统计学，临床和治疗结果因素以及健康的社会决定因素。多元回归分析发现，结核病治疗失败的最强预测因素是感染了其他疾病（OR 9.35; 95％CI 3.01–29.1），男性（OR 5.03; 95％CI 1.58-16.1），土库曼人种族（OR 11.0; 95％CI 2.00–60.1），结核病家族史（OR 0.21; 95％CI 0.05-0.96）和家庭人数（OR 1.21; 95％CI 0.99-1.48）。建议包括对患有其他疾病的患者进行更好的随访，并为他们的治疗提供便利，尤其是对于土库曼患者。

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