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首页> 外文期刊>Eastern Mediterranean Health Journal: Al-Magallat al-Sihhiyyat li-Sarq al-Mutawassit >Patients’ report of statins use and side-effects in a sample of hospitalized cardiac patients in the Islamic Republic of Iran
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Patients’ report of statins use and side-effects in a sample of hospitalized cardiac patients in the Islamic Republic of Iran

机译:伊朗伊斯兰共和国的住院心脏病患者样本中患者对他汀类药物使用和副作用的报告

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摘要

We aimed to study the prevalence of the side-effects of statins among Iranians patients admitted to a cardiac-specialized hospital and had taken statins prior to hospitalization. Data was collected between September 2007 and March 2008 and 200 patients were enrolled. A questionnaire was completed using the patients’ records and by interviewing the patients. The mean age of the participants was 61.5 (SD 12.3) years and 63% were males. The most commonly used statins was atrovastatin (99% of the patients). In all, 63.5% of the participants reported experiencing side-effects due to statins. The reported side-effects were respiratory (4%) and gastrointestinal effect (18.5%), headache (16.5%), rash (0.5%) and allergic reactions (5%); 9.5% reported muscle-related side-effects such as myalgia. Although, the clinical benefits outweigh the small risk of liver failure and myopathy, clinicians should be aware of the side-effects of statins.
机译:我们旨在研究在心脏专科医院就诊并在住院之前服用他汀类药物的伊朗患者中他汀类药物的副作用的患病率。在2007年9月至2008年3月之间收集了数据,招募了200名患者。通过使用患者记录并采访患者来完成问卷调查。参加者的平均年龄为61.5(SD 12.3)岁,男性为63%。最常用的他汀类药物是阿托伐他汀(99%的患者)。共有63.5%的参与者报告了他汀类药物引起的副作用。报告的副作用为呼吸道(4%)和胃肠道反应(18.5%),头痛(16.5%),皮疹(0.5%)和过敏反应(5%); 9.5%的人报告了肌肉相关的副作用,例如肌痛。尽管临床收益大于肝衰竭和肌病的小风险,但临床医生应意识到他汀类药物的副作用。

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