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Relationship between red cell distribution width and serum C reactive protein levels in maintenance hemodialysis patients

机译:维持性血液透析患者红细胞分布宽度与血清C反应蛋白水平的关系

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Relationship between red cell distribution width and serum C reactive protein levels in maintenance hemodialysis patients Ali Veysel Kara Department Of Nephrology, Erzincan Mengucek Gazi Research Hospital, Erzincan, Turkey INTRODUCTION: We aimed to investigate the relationship between RDW and serum CRP levels in maintenance hemodialysis patients. METHODS: We enrolled 112 eligible maintenance hemodialysis patients in this retrospective study. Two groups were identified according to red cell distribution width (RDW) values: patients with normal RDW (RDW 14.5%) and patients with elevated RDW (RDW ≥ 14.5%). Spearman correlation analysis and linear regression analysis were used to investigate the relationship between the study parameters. RESULTS: The only statistically significant difference between two groups was serum CRP levels (p: 0.007). Serum albumin levels had significant but weak inverse correlation with serum CRP levels (r: -0.257, p: 0.006). RDW values had significant but weak positive correlation with serum CRP levels (r: 0.289, p: 0.002). We did not found a significant correlation between hemoglobin levels and serum CRP levels and serum ferritin levels and serum CRP levels (p: 0.090 and p: 0.664, respectively). We made multivariate linear regression analysis and RDW was detected as the only independently associated factor for serum CRP levels (p: 0.028). DISCUSSION AND CONCLUSION: We found that there is a statistically significant positive correlation between CRP and RDW in maintenance hemodialysis patients. We also showed a significant relationship between RDW and serum CRP levels. We concluded that RDW can be used as an inflammatory marker for hemodialysis patients.
机译:维持性血液透析患者的红细胞分布宽度与血清C反应蛋白水平之间的关系土耳其埃尔兹坎市Erzincan Mengucek Gazi研究医院肾脏科Ali Veysel Kara简介:我们旨在研究维持性血液透析患者的RDW与血清CRP水平之间的关系。方法:我们纳入了112例符合条件的维持性血液透析患者。根据红细胞分布宽度(RDW)值分为两组:RDW正常的患者(RDW <14.5%)和RDW升高的患者(RDW≥14.5%)。 Spearman相关分析和线性回归分析用于研究研究参数之间的关系。结果:两组之间唯一的统计学差异是血清CRP水平(p:0.007)。血清白蛋白水平与血清​​CRP水平呈显着但弱的负相关(r:-0.257,p:0.006)。 RDW值与血清CRP水平呈显着正相关,但相关性较弱(r:0.289,p:0.002)。我们没有发现血红蛋白水平与血清​​CRP水平,血清铁蛋白水平和血清CRP水平之间存在显着相关性(分别为p:0.090和p:0.664)。我们进行了多元线性回归分析,RDW被检测为血清CRP水平的唯一独立相关因素(p:0.028)。讨论与结论:我们发现维持性血液透析患者的CRP与RDW之间存在统计学上的显着正相关。我们还显示RDW与血清CRP水平之间存在显着关系。我们得出的结论是,RDW可用作血液透析患者的炎症标志物。

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