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A case of primary Sj?gren?s syndrome with polyserositis

机译:原发性干燥综合征与多发性浆膜炎一例

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A case of primary Sj?gren?s syndrome with polyserositis Masashi Ohe 1 , Satoshi Hashino 2 , Kenzo Ohara 3 1 2 3 Sj?gren?s syndrome (SS) is an autoimmune disease with glandular and extraglandular manifestations. In terms of pulmonary and cardiac involvement, pleural and pericardial effusion are rare. Moreover, pleural effusion accompanied by pericardial effusion is very rare. We report a case of primary SS (pSS) presenting as pleural effusion, pericardial effusion and ascites. A 58-year-old woman was admitted to our hospital with a 2-week history of dyspnea. Bilateral pleural effusion, pericardial effusion and ascites were detected. Primary SS was diagnosed, based on xerophthalmia, xerostomia, positive results for the Shirmer test and anti-SS-A antibody, and abnormal salivary gland sialography. Pleural and pericardial effusions were attributed to autoimmunological inflammation and ascites was thought to be due to hyperinflammation-induced severe hypoalbuminemia. Treatment with high-dose corticosteroid was proved successful.
机译:一例原发性Sj?gren's综合征伴多发性浆膜炎Masashi Ohe 1 ,哈希敏(Satoshi Hashino) 2 ,小原贤三(skenoshi Ohara) 3 1 2 3 Sj?gren's综合征(SS)是一种具有腺体和腺外表现的自身免疫性疾病。就肺和心脏受累而言,胸膜和心包积液很少见。此外,胸膜积液伴有心包积液非常罕见。我们报告一例原发性SS(pSS)表现为胸腔积液,心包积液和腹水。一名58岁的女性因呼吸困难2周入院。检测到双侧胸腔积液,心包积液和腹水。根据干眼症,口腔干燥症,Shirmer试验和抗SS-A抗体的阳性结果以及唾液腺唾液管造影异常,诊断出原发性SS。胸膜和心包积液归因于自身免疫性炎症,并且腹水被认为是由于过度炎症引起的严重低蛋白血症。大剂量皮质类固醇治疗被证明是成功的。

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