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首页> 外文期刊>Iranian Journal of Neurology >Increased Guillain-Barre syndrome admissions in Shiraz, southern Iran
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Increased Guillain-Barre syndrome admissions in Shiraz, southern Iran

机译:伊朗南部设拉子的Guillain-Barre综合症住院人数增加

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BackgroundGuillain-Barre syndrome (GBS) is an acute immune-mediated peripheral neuropathy usually after an incident. This study was performed to investigate the basic epidemiologic features of GBS in south of Iran.MethodsWe studied consecutive patients with GBS in Nemazi Hospital of Shiraz, southern Iran. Demographic characteristics of the subjects, i.e. age, sex, and length of hospital stay were extracted. Information regarding yearly admissions for the entire hospital was also gathered. The prevalence of GBS per 10,000 hospital admissions was calculated and stratified by sex and year. Yearly prevalence was compared using the odds ratio (OR) and 95% confidence intervals (CI).ResultsFrom January 2000 to December 2009, 389 (232 males and 157 females) patients with GBS were admitted in our center. The mean age of patients was 29.8 ± 23.0 years and their mean length of hospital stay was 12.9 ± 11.6 days. The overall mortality rate was 6%. The ratio of admissions due to GBS to the total admissions was significantly higher in 2009, the year of an influenza A (H1N1) virus pandemic.ConclusionThere appears to be an increase in the incidence of GBS in Shiraz. This is in parallel with the increasing trend of some other autoimmune diseases.
机译:背景格林巴利综合征(GBS)是通常在事件发生后发生的一种急性免疫介导的周围神经病。这项研究旨在调查伊朗南部GBS的基本流行病学特征。方法我们在伊朗南部设拉子的Nemazi医院对连续的GBS患者进行了研究。提取受试者的人口统计学特征,即年龄,性别和住院时间。还收集了有关整个医院每年入院的信息。每10,000例住院患者中GBS的发生率按性别和年份进行了计算和分层。结果使用比值比(OR)和95%置信区间(CI)对年度患病率进行比较。结果从2000年1月至2009年12月,我们中心收治了389例GBS患者(232例男性和157例女性)。患者的平均年龄为29.8±23.0岁,平均住院时间为12.9±11.6天。总死亡率为6%。 2009年是甲型H1N1流感大流行年,GBS导致的入院人数占总入院人数的比例显着更高。结论在设拉子,GBS的发病率似乎有所增加。这与其他一些自身免疫性疾病的增加趋势并行。

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