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首页> 外文期刊>Eastern Mediterranean Health Journal: Al-Magallat al-Sihhiyyat li-Sarq al-Mutawassit >Cost–effectiveness of prescreening versus empirical vaccination for hepatitis A in Egyptian children with chronic liver disease
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Cost–effectiveness of prescreening versus empirical vaccination for hepatitis A in Egyptian children with chronic liver disease

机译：在埃及慢性肝病儿童中进行甲型肝炎的预筛查和经验接种的成本效益比较

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摘要

The aim of the study was to determine the prevalence of anti-hepatitis A virus (anti-HAV) antibodies among 172 children with chronic liver disease, and to calculate the cost–effectiveness of prescreening prior to hepatitis A vaccination. Anti-HAV antibodies were positive in 85.1%. However, seroprevalence of anti-HAV antibodies was 62.1% in children < 5 years and 94.4% in children 5+ years. We conclude that while it is cost-effective to do prescreening before hepatitis A vaccination for children with chronic liver disease aged 5+ years, prescreening might not be cost-effective in those aged < 5 years.
机译：该研究的目的是确定172名慢性肝病患儿中抗A型肝炎病毒（HAV）抗体的流行率，并计算甲型肝炎疫苗接种前进行预筛查的成本效益。抗HAV抗体阳性率为85.1％。然而，抗HAV抗体的血清阳性率在5岁以下的儿童中为62.1％，在5岁以上的儿童中为94.4％。我们得出的结论是，对于5岁以上的慢性肝病儿童，在进行甲型肝炎疫苗接种之前进行预筛查是合算的，但对于5岁以下的儿童而言，预筛查可能并不划算。

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