Faecal microbiota transplantation, a promising way to treat colorectal cancer

Yanru Ma; Haoyan Chen

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Faecal microbiota transplantation, a promising way to treat colorectal cancer

机译：粪便微生物群移植，一种治疗大肠癌的有前途的方法

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Colorectal cancer is the fourth most common morbidity worldwideand the second most common among women [1]. This diseaseis caused by both genetic and environmental factors, such ashigh-fat diet and disrupted gut microbiota [2]. Despite great advancesin cancer treatment options, drug resistance and insensitivityto treatment in patients with colorectal cancer necessitatethe development of effective therapeutic alternatives. In addition,an increasing number of studies have shown that the gut microbiotaplays a key role in the incidence and progression of colorectalcancer.

机译：结直肠癌是全球第四大常见发病率，在女性中第二多见[1]。这种疾病是由遗传和环境因素引起的，例如高脂饮食和肠道菌群破坏[2]。尽管在癌症治疗选择方面取得了很大的进步，但是对大肠癌患者的耐药性和对治疗的不敏感性仍需要开发有效的治疗选择。此外，越来越多的研究表明，肠道菌群在结直肠癌的发生和发展中起着关键作用。

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《EBioMedicine》 |2019年第2期|共2页
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Yanru Ma; Haoyan Chen;
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中图分类医用一般科学;
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1. Faecal microbiota transplantation in recurrent Clostridium difficile infection: Recommendations from the French Group of Faecal microbiota Transplantation [J] . Sokol Harry, Galperine Tatiana, Kapel Nathalie, Digestive and liver disease: official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver . 2016,第3期

机译：复发性艰难梭菌感染的粪便菌群移植：法国粪便菌群移植小组的建议
2. Faecal microbiota transplantation is promising but not a panacea [J] . Michael J. Sadowsky, Alexander Khoruts Nature Microbiology . 2016,第3期

机译：粪便微生物群移植很有希望，但不是万能药
3. Microbial taxonomic and metabolic alterations during faecal microbiota transplantation to treat Clostridium difficile infection [J] . Kellingray Lee, Le Gall Gwenaelle, Defernez Marianne, Journal of Infection . 2018,第2期

机译：粪便微生物群移植过程中微生物分类和代谢改变治疗梭菌差异感染
4. Circulating Cell-Free DNA-Based qMSP Demonstrates That Sydecan2 Methylation as a Promising Epigenetic Biomarker for Early Detection of Patients with Precancerous and Cancerous Colorectal Lesions [C] . Sungwhan An, TaeJeong Oh, Dongjun Jeong, Molecular Medicine TRI-CON. . 2014

机译：循环无细胞的DNA基QMSP证明了Sydecan2甲基化作为有望的表观遗传生物标志物，用于早期检测患癌前和癌细胞病患者的患者
5. Pro-Inflammatory and Genotoxic Bacterial Genes from the Intestinal Microbiota as Risk Factors for Colorectal Cancer [D] . Moreno, Ramon Gomez. 2018

机译：来自肠道微生物群的促炎和遗传毒性细菌基因作为结直肠癌的危险因素
6. Faecal microbiota transplantation a promising way to treat colorectal cancer [O] . Yanru Ma, Haoyan Chen 2019

机译：粪便微生物群移植一种治疗大肠癌的有前途的方法
7. P568. Alterations of Intestinal Microbiota in Ulcerative Colitis Patients Treated with Sequential Antibiotic Combination and Faecal Microbiota Transplantation [O] . 2015

机译：P568。顺序抗生素组合治疗溃疡性结肠炎患者肠道微生物患者的改变，粪便微生物移植治疗

Faecal microbiota transplantation, a promising way to treat colorectal cancer

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