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首页> 外文期刊>Iranian Journal of Neurology >Evaluation of non-motor symptoms and their impact on quality of life in patients with Parkinson’s disease, Isfahan, Iran
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Evaluation of non-motor symptoms and their impact on quality of life in patients with Parkinson’s disease, Isfahan, Iran

机译：伊朗伊斯法罕帕金森病患者的非运动症状及其对生活质量的影响评估

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Background: Parkinson’s disease (PD) is diagnosed on the basis of motor symptoms, but non-motor symptoms (NMS) have high prevalence in PD and often antecede motor symptoms for years and cause severe disability. This study was conducted to determine the prevalence of NMS in patients with PD.Methods: This cross-sectional study was performed in Isfahan, Iran, on patients with PD. The prevalence of NMS was evaluated by the NMS questionnaire, the NMS scale, and Parkinson's disease questionnaire-39 (PDQ-39). The Mini-Mental Status Examination (MMSE) was used for assessing cognition.Results: A total of 81 patients, including 60 men and 21 women, were recruited for this study. The prevalence of NMS was 100%, and the most commonly reported symptom was fatigue (87.7%); there was a strong correlation between NMS and the quality of life (QOL) of patients with PD (P < 0.001).Conclusion: This study showed that NMS are highly prevalent in the PD population and adversely affect QOL in these patients. Early diagnosis and treatment can improve QOL and can help in disability management of patients with PD.
机译：背景：帕金森氏病（PD）是根据运动症状诊断出来的，但非运动症状（NMS）的PD患病率很高，并且通常在运动症状发作之前已有多年，并导致严重的残疾。这项研究旨在确定PD患者中NMS的患病率。方法：这项横断面研究是在伊朗伊斯法罕进行的，针对PD患者。通过NMS问卷，NMS量表和帕金森氏病问卷-39（PDQ-39）评估了NMS的患病率。结果：本研究共招募了81名患者，包括60名男性和21名女性，其中包括迷你精神状态检查（MMSE）。 NMS的患病率为100％，最常报告的症状是疲劳（87.7％）。结论：这项研究表明，NMS在PD人群中非常普遍，并且对这些患者的QOL有负面影响（P <0.001）。早期诊断和治疗可以改善QOL，并有助于PD患者的残疾管理。

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