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首页> 外文期刊>Iranian Journal of Neurology >Investigating related factors with mortality rate in patients with postoperative meningitis: One longitudinal fallow-up study in Iran
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Investigating related factors with mortality rate in patients with postoperative meningitis: One longitudinal fallow-up study in Iran

机译：术后脑膜炎患者死亡率相关因素的调查：伊朗的一项纵向随访研究

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Background: Postoperative meningitis (POM) is the most dreaded cause of morbidity and mortality in neurosurgery patients. This study aimed to identify incidence and mortality rate as well as related factors to outcome in patients with POM.Methods: This descriptive longitudinal study conducted on patients with POM in duration of 2 years. Incidence and mortality rates as well as related factors were studied.Results: The incidence and mortality rates of POM was 8.9% and 50%, respectively. There were statistically significant association between male gender, as well as having mechanical ventilation, and death outcome in univariable analysis. In addition, in multivariable logistic regression analysis, length of intensive care unit (ICU) stay of more than 7 days [Odds ratio (OR): 1.2, confidence interval of 95% (95%CI): 1.02-6.2), mechanical ventilation (OR: 1.1, 95%CI: 1.05-5.1], positive cerebrospinal fluid (CSF) culture (OR: 2.4, 95%CI: 1.9-4.08) were predicting factors to death outcome. Finally, we found an inverse relationship between survival function and length of ICU stay in patients with POM.Conclusion: According to the high rates of incidence and mortality due to POM in this study, preventive studies to decrease this dreaded cause of morbidity and mortality in neurosurgery patients should be the planned.
机译：背景：术后脑膜炎（POM）是神经外科患者发病和死亡的最可怕原因。这项研究旨在确定POM患者的发病率和死亡率以及影响预后的相关因素。方法：这项描述性纵向研究针对2年间POM患者进行。结果：POM的发生率和死亡率分别为8.9％和50％。在单变量分析中，男性，有机械通气和死亡结局之间存在统计学上的显着关联。此外，在多变量logistic回归分析中，重症监护病房（ICU）的住院时间超过7天[赔率（OR）：1.2，95％（95％CI）的置信区间：1.02-6.2），机械通气（OR：1.1，95％CI：1.05-5.1），脑脊液（CSF）培养阳性（OR：2.4、95％CI：1.9-4.08）是死亡结果的预测因素，最后，我们发现生存与生存率成反比结论：根据本研究中POM引起的高发病率和高死亡率，应计划进行预防性研究以减少神经外科患者发病率和死亡率的可怕原因。

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