Low-Dose Acetylsalicylic Acid Use and the Risk of Upper Gastrointestinal Bleeding: A Meta-Analysis of Randomized Clinical Trials and Observational Studies

Valkhoff Vera E; Sturkenboom Miriam CJM; Hill Catherine; Veldhuyzen van Zanten Sander; Kuipers Ernst J

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Low-Dose Acetylsalicylic Acid Use and the Risk of Upper Gastrointestinal Bleeding: A Meta-Analysis of Randomized Clinical Trials and Observational Studies

机译：低剂量乙酰水杨酸的使用和上消化道出血的风险：一项随机临床试验和观察性研究的荟萃分析

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BACKGROUND Low-dose acetylsalicylic acid (LDA, 75 mg/day to 325 mg/day) is recommended for primary and secondary prevention of cardiovascular events, but has been linked to an increased risk of upper gastrointestinal bleeding (UGIB).

机译：背景技术低剂量的乙酰水杨酸（LDA，75 mg /天至325 mg /天）被推荐用于心血管事件的一级和二级预防，但与上消化道出血（UGIB）的风险增加有关。

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《ISRN Hypertension》 |2013年第3期|共9页
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Valkhoff Vera E; Sturkenboom Miriam CJM; Hill Catherine; Veldhuyzen van Zanten Sander; Kuipers Ernst J;
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中图分类心血管疾病;
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1. Low-dose acetylsalicylic acid use and the risk of upper gastrointestinal bleeding: A meta-analysis of randomized clinical trials and observational studies. [J] . Vera E Valkhoff, Miriam Sturkenboom, Catherine Hill, Canadian journal of gastroenterology . 2013,第3期

机译：低剂量乙酰水杨酸的使用和上消化道出血的风险：一项随机临床试验和观察性研究的荟萃分析。
2. Burden of upper gastrointestinal symptoms in patients receiving low-dose acetylsalicylic acid for cardiovascular risk management: A prospective observational study [J] . BytzerP., PrattS., ElkinE., American journal of cardiovascular drugs: drugs, devices, and other interventions . 2013,第1期

机译：低剂量乙酰水杨酸用于心血管风险管理的患者的上消化道症状负担：一项前瞻性观察性研究
3. Mortality in patients who discontinue low-dose acetylsalicylic acid therapy after upper gastrointestinal bleeding [J] . Gonzalez-Perez Antonio, Eugenia Saez Maria, Johansson Saga, Pharmacoepidemiology and drug safety . 2017,第2期

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4. Application of perioperative immunonutrition for gastrointestinal surgery: a meta-analysis of randomized controlled trials [C] . Yamin Zheng, Fei Li, Baoju Qi, 国际营养科学联盟第八届临床营养学大会暨第五届亚太临床营养学会大会 . 2006

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5. Evaluating bias caused by screening in observational risk-factor studies of lung cancer nested in the PLCO randomized screening trial. [D] . Jansen, Rick Jeffrey. 2009

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6. Low-dose acetylsalicylic acid use and the risk of upper gastrointestinal bleeding: A meta-analysis of randomized clinical trials and observational studies [O] . Vera E Valkhoff, Miriam CJM Sturkenboom, Catherine Hill, 2013

机译：低剂量乙酰水杨酸的使用和上消化道出血的风险：一项随机临床试验和观察性研究的荟萃分析
7. PCV141 UPPER GASTROINTESTINAL SYMPTOMS IN PATIENTS WITH CARDIOVASCULAR RISK TAKING LOW-DOSE ACETYLSALICYLIC ACID: AN OBSERVATIONAL STUDY [O] . Sörstadius E, Thompson VJ, Pratt SE, 2009

机译：服用低剂量乙醛酸的心血管疾病患者PCV141上消化道症状的观察

Low-Dose Acetylsalicylic Acid Use and the Risk of Upper Gastrointestinal Bleeding: A Meta-Analysis of Randomized Clinical Trials and Observational Studies

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