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首页> 外文期刊>e-Jurnal Medika Udayana >CLOZAPINE ON PARANOID SCHIZOPHRENIA WITH OBESITY: A CASE REPORT
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CLOZAPINE ON PARANOID SCHIZOPHRENIA WITH OBESITY: A CASE REPORT

机译：氯氮平治疗肥胖型胰腺分裂症：病例报告

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Treatments of schizophrenia using atypical antipsychotics provide remission of symptoms and side effects differ between individuals. The use of the method by finding the right medication often has an impact on patient adherence to treatment. In the case of a female patient aged 26 years was diagnosed with paranoid schizophrenia and clozapine treatment using 2x25 mg for 6 months. Schizophrenic symptoms had subsided and the patient can work, but the treatment was stopped by the parents. Treatment was discontinued because of patient body weight increased to 80 kg from initial weight 65 kg. Clozapine increases the weight by several mechanisms. Genetic and environmental influences susceptibility to gain weight. Weight gain can also cause a large enough increase in obesity-related comorbidities and health risks such as type II diabetes mellitus, hypertension, hear t disease and cancer. Subsequent treatment be changed using atypical antipsychotics risperidone at a dose equivalent. Given also educate and maintain compliance with treatment.
机译：使用非典型抗精神病药治疗精神分裂症可缓解症状，且副作用因人而异。通过找到正确的药物使用该方法通常会影响患者对治疗的依从性。对于26岁的女性患者，诊断为偏执型精神分裂症和氯氮平治疗，使用2x25 mg治疗6个月。精神分裂症症状已消退，患者可以工作，但父母停止了治疗。由于患者体重从最初的65公斤增加到80公斤，因此中止了治疗。氯氮平通过多种机制增加体重。遗传和环境影响体重增加的敏感性。体重增加还可能导致与肥胖相关的合并症和健康风险大幅增加，例如II型糖尿病，高血压，听力障碍和癌症。使用非典型抗精神病药利培酮以等价剂量更改后续治疗。给予也教育并保持对治疗的依从性。

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