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首页> 外文期刊>Iranian Journal of Radiology >DIFFUSIONWEIGHTED IMAGING IN ACUTE ATTACKS OF MULTIPLE SCLEROSIS
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DIFFUSIONWEIGHTED IMAGING IN ACUTE ATTACKS OF MULTIPLE SCLEROSIS

机译：多发性硬化症急性发作中的扩散加权成像

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Background: Multiple sclerosis (MS) is one of the most common autoimmune disorders of the central nervous system. In spite of various imaging modalities, the definitive diagnosis of MS remains challenging.Objectives: This study was designed to evaluate the usefulness of diffusion weighted imaging (DWI) in the diagnosis of acute MS attack and to compare its results with contrast enhanced MRI (CE-MRI).Patients and Methods: In this cross sectional study, seventy patients with definite diagnosis of relapsing-remitting MS were included.CE-MRI using 0.1 mmol/kg gadolinium as well as DWI sequences were performed for all patients. The percentage of patients with positive DWI was compared with the results of CE-MRI and the consistency between the two imaging modalities was evaluated.Moreover, the relationship between the time of onset of patient’s symptoms and test results for both methods were investigated.Results: CE-MRI yielded positive results for 61 (87%) patients and DWI yielded positive for 53 (76%) patients. In fifty patients (71.42%), both tests were positive and in six cases (8.57%), both were negative. The test results of three patients turned out to be positive in DWI, while they tested negative in CE-MRI. There was no significant relationship between the results of CE-MRI as well as DWI and the time of imaging from the onset of symptoms.Conclusion: These data indicate that while CE-MRI will depictmorepositive results, there are cases inwhichDWI willshowa positive result while CE-MRI is negative.We suggest that the combination of these two imaging modalities might yield more positive results in diagnosing acute MS attack giving rise to a more accurate diagnosis.
机译：背景：多发性硬化症（MS）是中枢神经系统最常见的自身免疫性疾病之一。尽管有多种成像方式，但MS的明确诊断仍具有挑战性。目的：本研究旨在评估弥散加权成像（DWI）在诊断急性MS发作中的实用性，并将其结果与对比增强MRI（CE）进行比较患者和方法：在这项横断面研究中，纳入了70例确诊为复发缓解型MS的患者。所有患者均使用0.1 mmol / kg CE和DWI序列进行了CE-MRI。将DWI阳性患者的百分比与CE-MRI结果进行比较，评估两种影像学方法之间的一致性，并且研究两种方法的患者症状发作时间与测试结果之间的关系。 CE-MRI对61例（87％）患者产生阳性结果，而DWI对53例（76％）患者产生阳性结果。在五十名患者（71.42％）中，两项检查均呈阳性，而六名患者（8.57％）均为阴性。三名患者的检查结果在DWI中呈阳性，而在CE-MRI中呈阴性。结论：这些数据表明，尽管CE-MRI将显示更多阳性结果，但在某些情况下，DWI将显示阳性结果，而CE显示MRI和DWI与症状发作时间之间无显着关系。 -MRI阴性。我们建议，这两种成像方式的组合在诊断急性MS发作方面可能会产生更多阳性结果，从而使诊断更加准确。

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