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首页> 外文期刊>Iranian Journal of Reproductive Medicine >COMPARISON OF NUCLEATED RED BLOOD CELLS IN THE UMBILICAL CORD OF TERM NEONATES IN HEALTHY WOMEN AND WOMEN WITH PREECLAMPSIA
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COMPARISON OF NUCLEATED RED BLOOD CELLS IN THE UMBILICAL CORD OF TERM NEONATES IN HEALTHY WOMEN AND WOMEN WITH PREECLAMPSIA

机译：健康妇女和有青光眼妇女的新生儿新月经脐带核红色血细胞的比较

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Background: Asphyxia is a common cause of perinatal mortality in 5-10% of all births worldwide. The present parameters for determining perinatal asphyxia, e.g. preeclampsia, cannot be considered as markers per se, and require auxiliary markers, e.g. increased number of nucleated red blood (NRBC) cells, for early diagnosis of perinatal asphyxia.Objective: In this study, we evaluated the mean NRBC count in preeclampsia and to determine the usefulness of the NRBC as independent prognostic factors of perinatal complications.Materials and Methods: This was a cross-sectional study in order to compare the NRBC in the umbilical cord of term neonates born to 50 mothers with preeclampsia and 150 normal mothers. The exclusion criteria were mothera€?s affliction with complications of pregnancy and inexact last menstrual period. The variables under study were maternal and neonatal data. The count of NRBC was determined with standard laboratory procedures in the blood samples from umbilical cord of the neonates. The acquired data were fed into SPSS 16 software and analyzed using statistical tests.Results: The mean value of NRBC count was significantly higher in preeclamptic women (p0.0001). The average 1st and 5th minute Apgar scores were significantly higher in normal mothers (p0.001).Conclusion: Increase of NRBC in neonates born to mothers with preeclampsia may be due to chronic hypoxia, this group of neonates have increased risk and require more precise and extensive care during delivery and after birth in order to have reduced mortality and complications during the neonatal period.
机译：背景：窒息是围产期死亡的普遍原因，占全球所有出生的5-10％。用于确定围产期窒息的当前参数，例如子痫前期本身不能被认为是标志物，需要辅助标志物，例如目的：本研究评估先兆子痫患者的平均NRBC计数，并确定NRBC作为围产期并发症的独立预后因素的有用性。方法：这是一项横断面研究，目的是比较50名先兆子痫母亲和150名正常母亲的足月新生儿的脐带NRBC。排除标准是母亲患有妊娠并发症和上月经不准确的痛苦。研究中的变量是孕产妇和新生儿数据。 NRBC的计数是通过标准实验室程序从新生儿脐带血样本中测定的。结果：子痫前期妇女的NRBC计数平均值显着更高（p <0.0001）。正常母亲在第1分钟和第5分钟的平均Apgar评分显着较高（p <0.001）。结论：先兆子痫母亲所生新生儿的NRBC升高可能是由于慢性缺氧所致，这组新生儿的风险增加，需要更精确的诊断。在分娩期间和分娩后进行广泛护理，以降低新生儿期的死亡率和并发症。

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