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首页> 外文期刊>Iranian Journal of Reproductive Medicine >PREDICTIVE FACTORS INFLUENCING PREGNANCY RATES AFTER INTRAUTERINE INSEMINATION
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PREDICTIVE FACTORS INFLUENCING PREGNANCY RATES AFTER INTRAUTERINE INSEMINATION

机译：宫内节育后影响妊娠率的预测因素

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Background: So far, many studies investigated factors that affect pregnancy rates after intrauterine insemination (IUI). Various investigators have not agreed on the nature and ranking of these criteria. Objective: The aim of this study was to assess the predictive factors for pregnancy rate after controlled ovarian hyperstimulation (COH)/ IUI.Materials and Methods: Retrospective study of all patients undergoing IUI at Zeynep Kamil Gynecologic and Pediatric Training and Research Hospital from January 2006 to December 2009. In total 980 IUI cycles in 569 couples were analyzed. All women in the study underwent ovarian stimulation using gonadotropin and IUI was performed 36 h after triggering ovulation. The primary outcome measure was clinical pregnancy rates. Predictive factors evaluated were female age, body mass index (BMI), duration of infertility, type of infertility, follicle stimulating hormone (FSH) level and estradiol (E2) on third day of the cycle, number of preovulatory follicles, endometrial thichness, total motil sperm (TMS) count, and ratio of progressive motile sperm.Results: The overall clinical pregnancy rate was 4.7%. Among the predictive factors after multivariate logistic regression analysis level of BMI (25 kg/m?2), number of preovulatory follicles ( ?32), level of FSH (9.4 IU/L), level of E2 (80 pg/ml) and the ratio of progressive motile sperm (50%) significantly influenced the clinical pregnancy rate.Conclusion: Level of BMI, FSH, estradiol, number of preovulatory follicles and the ratio of progressive motile sperm may determine IUI procedure as optimum treatment model.
机译：背景：到目前为止，许多研究调查了影响子宫内授精（IUI）后妊娠率的因素。各种研究人员尚未就这些标准的性质和等级达成共识。目的：本研究旨在评估控制性卵巢过度刺激（COH）/ IUI后妊娠率的预测因素。材料与方法：2006年1月以来在Zeynep Kamil妇科和儿科培训研究医院接受IUI的所有患者的回顾性研究到2009年12月。共分析了569对夫妇的980个IUI周期。该研究中的所有妇女均使用促性腺激素进行了卵巢刺激，并且在触发排卵后36小时进行了IUI。主要结果指标是临床妊娠率。评估的预测因素是女性年龄，体重指数（BMI），不孕持续时间，不孕类型，周期第三天的卵泡刺激素（FSH）水平和雌二醇（E2），排卵前卵泡数，子宫内膜厚度，总结果：临床总妊娠率为4.7％。在多元logistic回归分析后的预测因素中，BMI水平（<25 kg / m？2），排卵前卵泡数（？32），FSH水平（<9.4 IU / L），E2水平（<80 pg /结论：BMI，FSH，雌二醇，排卵前卵泡数和进行性活动精子的比例可能决定IUI手术为最佳治疗模型。

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