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首页> 外文期刊>Iranian Journal of Reproductive Medicine >COMPARISON OF DEVELOPMENTAL STATUS OF 5-YEAR-OLD SINGLETON CHILDREN BORN THROUGH ASSISTED AND NATURAL CONCEPTIONS
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COMPARISON OF DEVELOPMENTAL STATUS OF 5-YEAR-OLD SINGLETON CHILDREN BORN THROUGH ASSISTED AND NATURAL CONCEPTIONS

机译：附助与自然观念的5岁单胎儿童出生发育状况比较

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Background: Approximately one percent of current live births of the world are conceived via assisted reproductive technologies (ART).Objective: The purpose of this study was to compare the developmental status of children born through assisted and natural conceptions at the age of five years.Materials and Methods: In a retrospective cohort study, developmental status of 5 years old children was evaluated via Persian version of 60-month Ages and Stages Questionnaires. Case group consisted of 61 singletons, term babies whom were born through ART in the Research and Clinical Center for Infertility, Yazd, Iran in 2005. Control group consisted of 61 term, first child, singleton and spontaneously conceived born five years old children whom were referred to Shahid Akbari primary health care center in 2010.Results: 58 girls (47.5%) and 64 boys (52.5%) were evaluated. Frequency of developmental delay in domains of fine motor (47.5% vs. 24.6%, p=0.008) and problem solving (60.6% vs. 34.4%, p=0.004) were more in ART born children. On logistic regression, fine motor development state was independently affected by maternal educational level (OR: 5.3, 95% CI: 1.67-16.30, p=0.004) and developmental status in problem solving domains was independently affected by maternal educational level (OR: 4.88, 95% CI: 1.25-19.07, p=0.02) and birth weight (OR: 7.1, 95% CI: 1.78-29.01, p=0.006).Conclusion: Maternal educational level and birth weight are important factors that influenced developmental outcome of ART born children.
机译：背景：世界上大约有百分之一的活产是通过辅助生殖技术（ART）进行的。目的：本研究的目的是比较五岁时通过辅助和自然观念出生的儿童的发育状况。材料和方法：在一项回顾性队列研究中，通过波斯语版的60个月年龄和阶段问卷对5岁儿童的发育状况进行了评估。病例组由61名单胎，足月婴儿组成，这些婴儿是2005年在伊朗亚兹德的不孕症研究和临床中心通过ART出生的。对照组由61名足月，第一胎，单胎和自然怀孕的五岁儿童组成。结果在2010年送达Shahid Akbari初级卫生保健中心。结果：对58名女孩（47.5％）和64名男孩（52.5％）进行了评估。在ART出生的儿童中，精细运动领域发育延迟的频率（47.5％vs. 24.6％，p = 0.008）和解决问题的频率（60.6％vs. 34.4％，p = 0.004）更多。在逻辑回归上，精细运动发育状态受母亲教育水平的独立影响（OR：5.3，95％CI：1.67-16.30，p = 0.004），解决问题领域的发展状况受母亲教育水平的独立影响（OR：4.88） ，95％CI：1.25-19.07，p = 0.02）和出生体重（OR：7.1，95％CI：1.78-29.01，p = 0.006）。结论：母亲的教育水平和出生体重是影响婴儿发育结局的重要因素。 ART出生的孩子。

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