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首页> 外文期刊>EFSA Journal >Scientific Opinion on the safety and efficacy of zinc compounds (E6) as feed additives for all animal species (zinc acetate, dihydrate; zinc chloride, anhydrous; zinc oxide; zinc sulphate, heptahydrate; zinc sulphate, monohydrate; zinc chelate of amino acids, hydrate; zinc chelate of glycine, hydrate), based on a dossier submitted by FEFANA asbl
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Scientific Opinion on the safety and efficacy of zinc compounds (E6) as feed additives for all animal species (zinc acetate, dihydrate; zinc chloride, anhydrous; zinc oxide; zinc sulphate, heptahydrate; zinc sulphate, monohydrate; zinc chelate of amino acids, hydrate; zinc chelate of glycine, hydrate), based on a dossier submitted by FEFANA asbl

机译:关于锌化合物(E6)作为所有动物饲料添加剂的安全性和有效性的科学意见(醋酸锌,二水合物;无水氯化锌;氧化锌;硫酸锌,七水合物;硫酸锌,一水合物;氨基酸螯合锌,水合物;甘氨酸的锌螯合物,水合物),基于FEFANA asbl提交的档案

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The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) has assessed seven zinc compounds in the current application: zinc acetate, dihydrate; zinc chloride, anhydrous; zinc oxide; zinc sulphate, heptahydrate; zinc sulphate, monohydrate; zinc chelate of amino acids, hydrate; zinc chelate of glycine, hydrate. These compounds are safe sources of zinc for all animal species/categories when used up to maximum authorised zinc levels in feed; the simultaneous use of both feed and water supplemented with zinc should be avoided. No concerns for consumer safety are expected from the use of the zinc compounds under application when used up to the maximum authorised levels in feed. Zinc acetate, zinc sulphate (heptahydrate and monohydrate), zinc chelate of amino acids, hydrate, and zinc chelate of glycine, hydrate, are irritant to the skin, eyes and mucosae. Zinc sulphate may cause skin sensitisation. Zinc chloride, anhydrous, is extremely corrosive to skin, eyes and mucosae. Zinc chelate of amino acids, hydrate, may induce sensitisation by inhalation and should be considered a skin sensitiser. Zinc oxide is not irritant to skin or eyes or skin sensitiser. The Panel considers that all the additives under application should be treated as hazardous by inhalation. The use of the zinc compounds under assessment does not pose an immediate concern for the agricultural soil compartment. However, there is a potential environmental concern related to drainage and the runoff of zinc to surface water, with acidic sandy soils being the most vulnerable; for a final conclusion, further refinements to the assessment of zinc‐based additives in livestock need to be considered, and additional data are required. The adoption of the newly proposed maximum zinc contents in feeds would greatly reduce the risk to the environment from zinc‐containing additives. The zinc compounds under assessment are efficacious in meeting animal requirements.
机译:动物饲料中使用的添加剂和产品或物质小组(FEEDAP)已评估了当前应用中的七种锌化合物:乙酸锌,二水合物;无水氯化锌;氧化锌七水合硫酸锌;一水合硫酸锌;氨基酸锌螯合物,水合物;甘氨酸锌螯合物,水合物。当在饲料中使用的锌含量达到最高允许水平时,这些化合物是所有动物物种/类别中锌的安全来源。应避免同时使用补锌的饲料和水。当所使用的锌化合物用量达到饲料中的最大允许水平时,预计不会对消费者的安全造成任何影响。醋酸锌,硫酸锌(七水合物和一水合物),氨基酸螯合物的锌螯合物,水合物和甘氨酸的螯合物(水合物)对皮肤,眼睛和粘膜有刺激性。硫酸锌可能引起皮肤过敏。无水氯化锌对皮肤,眼睛和粘膜有极强的腐蚀性。氨基酸,水合物的锌螯合剂可能通过吸入引起敏化作用,应被认为是皮肤敏化剂。氧化锌对皮肤或眼睛或皮肤过敏剂无刺激性。小组认为,所有正在使用的添加剂均应通过吸入处理视为危险。被评估的锌化合物的使用并未引起农业土壤隔间的直接关注。然而,潜在的环境问题涉及排水和锌向地表水的径流,酸性沙质土壤是最脆弱的;为了得出最终结论,需要考虑进一步改进牲畜中锌基添加剂的评估,并需要其他数据。在饲料中采用新提议的最大锌含量将大大降低含锌添加剂对环境的危害。被评估的锌化合物可有效满足动物需求。

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