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Analysis of possible foodutrient and drug interactions in hospitalized patients

机译：住院患者可能的食物/营养和药物相互作用分析

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ABSTRACTObjective:To evaluate the prescription in relation to the possible interactions between drugs and foodsutrients in the diets of patients in the Hospital Regional Justino Luz in the municipality of Picos, Piauí, Brazil.Methods:The sample consisted of 60 medical records of patients admitted at the hospital. The records were analyzed according to the presence or absence of interactions between drugs and foodsutrients of the prescribed diets.Results:Of the 82 drugs prescribed in all periods, there were 16 drugs (19.5%) with possible interaction with food, a total of 60 interactions between nutrient/food and medicine. Thus, 18 (30%), 10 (17%) and 8 (13%) possible interactions were identified with captopril (cardiovascular drug) with acetylsalicylic acid (anti-inflammatory) and spironolactone (diuretic), respectively representing the highest numbers of interactions among the classes of investigated drugs. It was also found that the total interactions between foodutrients and drugs, 32 (53%) accounted for interactions with cardiovascular drugs, 13 (22%) with anti-inflammatory drugs, 11 (18%) with diuretic agents e 4 (7%) with drugs that act on the digestive tract.Conclusion:There was a high number of interactions between foodutrients and medicines emphasizing the need for prior knowledge of these interactions as a way to avoid impairment in the treatment, longer hospital stays and/or damage to the nutritional status of the patients.
机译：摘要：目的：评估与巴西皮奥伊州皮科斯市地区医院Justino Luz的患者饮食中药物与食物/营养素之间可能相互作用有关的处方。方法：样本包括60例患者的医疗记录在医院住院。根据处方与饮食之间药物与食物/营养物质之间是否存在相互作用进行记录分析。结果：在所有时期内，在处方的82种药物中，有16种药物（19.5％）与食物可能相互作用，总计营养/食物与药物之间的60种相互作用因此，确定卡托普利（心血管药物）与乙酰水杨酸（抗炎药）和螺内酯（利尿剂）的相互作用分别为18（30％），10（17％）和8（13％），分别代表了最高的相互作用次数在被调查药物的类别中。还发现，食物/营养物与药物之间的总相互作用为32（53％）与心血管药物相互作用，13（22％）与抗炎药相互作用，11（18％）与利尿剂e 4（7结论：食物/营养素与药物之间存在大量的相互作用，强调需要事先了解这些相互作用，从而避免治疗受损，更长的住院时间和/或损害患者的营养状况。

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