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首页> 外文期刊>Egyptian Journal of Anaesthesia >Postoperative analgesia after major abdominal surgery: Fentanyl–bupivacaine patient controlled epidural analgesia versus fentanyl patient controlled intravenous analgesia
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Postoperative analgesia after major abdominal surgery: Fentanyl–bupivacaine patient controlled epidural analgesia versus fentanyl patient controlled intravenous analgesia

机译：大腹部手术后的术后镇痛：芬太尼-布比卡因患者控制的硬膜外镇痛与芬太尼患者控制的静脉镇痛

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Background Major abdominal surgeries induce neurohumoral changes responsible for postoperative pain, various organ dysfunctions and prolonged hospitalization. Inadequate pain control is harmful and costly to patients thus an appropriate pain therapy to those patients must be applicated. Methods One hundred patients (ASA I or II) of either sex aged from 20 to 60 years were scheduled for elective major abdominal surgery. Patients were allocated randomly into two groups (fifty patients each) to receive: patient-controlled epidural analgesia with bupivacaine 0.125% and fentanyl (PCEA group), or patient controlled intravenous analgesia with fentanyl (PCIA group). Postoperative pain was assessed over 24 h using Numerical Pain Rating scale (NPRS). The frequency of rescue analgesia, sedation score and overall patient satisfaction were recorded. Any concomitant events like nausea; vomiting, shivering, pruritus or respiratory complications were recorded postoperatively. Results There was a significant less pain in PCEA group at 2, 8 and 12 h. postoperative but PCIA group had less pain at immediate postoperative time. As regard sedation scale, patients of the PCEA group were significantly less sedated than PCIA group at immediate postoperative only. Overall patient satisfaction was significantly more in PCEA group. Conclusion This study concluded that both PCEA and PCIA were effective in pain relief after major abdominal surgery but PCEA was much better in pain relief, less sedating effect and overall patient satisfaction.
机译：背景大型腹部手术会引起神经体液变化，从而引起术后疼痛，各种器官功能障碍和住院时间延长。疼痛控制不当对患者有害且代价高昂，因此必须对患者实施适当的疼痛治疗。方法选择年龄在20至60岁之间的一百名男女（ASA I或II型）进行择期大腹部手术。将患者随机分为两组（每组50名患者）接受：0.125％布比卡因和芬太尼的患者自控硬膜外镇痛（PCEA组）或芬太尼（PCIA组）进行患者自控静脉镇痛。使用数字疼痛评定量表（NPRS）评估术后24小时的疼痛。记录急救镇痛的频率，镇静分数和总体患者满意度。任何伴随出现的恶心事件;术后记录呕吐，发抖，瘙痒或呼吸系统并发症。结果PCEA组在第2、8和12 h疼痛明显减轻。术后，但PCIA组术后立即疼痛减轻。就镇静程度而言，仅在术后即刻，PCEA组患者的镇静作用明显少于PCIA组。 PCEA组的总体患者满意度明显更高。结论本研究得出结论，PCEA和PCIA均能在腹部大手术后缓解疼痛，但PCEA在缓解疼痛，镇静效果和总体患者满意度方面要好得多。

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