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A new era of thromboelastometry

机译:血栓弹力测定的新时代

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Severe hemorrhage with necessity of allogeneic blood transfusion is common complication in intensive care unit and is associated with increased morbidity and mortality. Prompt recognition and treatment of bleeding causes becomes essential for the effective control of hemorrhage, rationalizing the use of allogeneic blood components, and in this way, preventing an occurrence of their potential adverse effects. Conventional coagulation tests such as prothrombin time and activated partial thromboplastin time present limitations in predicting bleeding and guiding transfusion therapy in critically ill patients. Viscoelastic tests such as thromboelastography and rotational thromboelastometry allow rapid detection of coagulopathy and goal-directed therapy with specific hemostatic drugs. The new era of thromboelastometry relies on its efficacy, practicality, reproducibility and cost-effectiveness to establish itself as the main diagnostic tool and transfusion guide in patients with severe active bleeding.
机译:严重的出血和必须进行异体输血是重症监护病房的常见并发症,并与发病率和死亡率增加相关。及时识别和治疗出血原因对于有效控制出血,合理使用同种异体血液成分以及以这种方式防止其潜在不良反应的发生至关重要。常规凝血测试(例如凝血酶原时间和活化的部分凝血活酶时间)在预测重症患者的出血和指导输血治疗方面存在局限性。诸如血栓弹力图和旋转血栓弹力测定法等粘弹性测试可以快速检测凝血病并使用特定的止血药物进行目标导向的治疗。血栓弹力测定的新时代依赖于它的功效,实用性,可重复性和成本效益,使其成为严重活动性出血患者的主要诊断工具和输血指南。

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