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Assessment of clinical and epidemiological characteristics of patients with and without sepsis in intensive care units of a tertiary hospital

机译：三级医院重症监护病房有无败血症患者的临床和流行病学特征评估

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Objective To describe the clinical and epidemiological features of patients with and without sepsis at critical care units of a public hospital. Methods A cross-sectional study was carried out from May 2012 to April 2013. Clinical and laboratory data of patients with and without sepsis in the intensive care units were reviewed of medical records. Results We evaluated 466 patients, 58% were men, median age was 40 years, and 146 (31%) of them were diagnosed with sepsis. The overall mortality was 20% being significantly higher for patients with sepsis (39%). The factors associated with intensive care unit mortality were the presence of sepsis (OR: 6.1, 95%CI: 3.7-10.5), age (OR: 3.6, 95%CI: 1.4-7.2), and length of hospital stay (OR: 0.96, 95%CI: 0.94-0.98). Pulmonary (49%) and intra-abdominal (20%) infections were most commonly identified sites, and coagulase-negative staphylococci and enteric Gram negative bacilli the most frequent (66%) pathogens isolated. Conclusion Although the impact of sepsis on mortality is related to patients’ clinical and epidemiological characteristics, a critical evaluation of these data is important since they will allow the direct implementation of local policies for managing this serious public health problem.
机译：目的描述公立医院重症监护室有无败血症患者的临床和流行病学特征。方法对2012年5月至2013年4月的横断面研究进行回顾性分析。结果我们评估了466名患者，其中58％为男性，中位年龄为40岁，其中146名（31％）被诊断患有败血症。败血症患者的总死亡率为20％，显着更高（39％）。与重症监护病房死亡率相关的因素包括败血症的存在（OR：6.1，95％CI：3.7-10.5），年龄（OR：3.6，95％CI：1.4-7.2）和住院时间（OR： 0.96，95％CI：0.94-0.98）。肺部感染（49％）和腹腔感染（20％）是最常见的部位，而凝固酶阴性葡萄球菌和肠道革兰氏阴性杆菌是最常见的病原体（66％）。结论尽管败血症对死亡率的影响与患者的临床和流行病学特征有关，但是对这些数据进行严格评估仍然很重要，因为它们将允许直接实施当地政策来解决这一严重的公共卫生问题。

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