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Hormonal and metabolic substrate status in response to exercise in men of different phenotype

机译:不同表型男性对运动反应的激素和代谢底物状态

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Objectives The present study verified the effect of moderate-to-high-intensity aerobic exercise on the endocrine response profile and adipose tissue in young healthy men with different phenotype characteristics. Design Eighteen men were divided into three experimental groups with defined body components and specific physical fitness: Endurance phenotype – EP ( n ?=?6; low body mass; low fat content; aerobic endurance trained), Athletic phenotype – AP ( n ?=?6; high body mass; low fat content, resistance trained), Obesity phenotype – OP ( n ?=?6; high body mass; high fat content, untrained). Methods The participants performed an progressive exercise protocol on a treadmill (30% VO _(2max), 50% VO _(2max), 70% VO _(2max)), separated by 45?s of passive rest for blood collection. Results Plasma glucose oxidation increased in relation to exercise intensity, but to a greater extent in the AP group. The free fatty acids’ plasma level decreased with a rise in exercise intensity, but with different kinetics in particular phenotypes. Plasma growth hormone increased after the cessation of exercise and was significantly higher in all groups 45?min into recovery compared to resting values. Plasma insulin decreased during exercise in all groups, but in the OP, the decrease was blunted. Conclusions The results indicate that the rate of lipolysis, hormonal and metabolic response to aerobic exercise depends on the individuals’ phenotype. Thus, exercise type, duration and intensity have to be strictly individualized in relation to phenotype in order to reach optimal metabolic benefits.
机译:目的本研究验证了中度至高强度有氧运动对具有不同表型特征的年轻健康男性的内分泌反应谱和脂肪组织的影响。设计将18名男性分为具有定义的身体成分和特定身体素质的三个实验组:耐力表型– EP(n = 6,体重低;低脂肪;有氧耐力训练),运动表型– AP(n = ?6;高体重;低脂肪含量,受过抵抗训练),肥胖表型-OP(n?=?6;高体重;高脂肪含量,未受过训练)。方法参与者在跑步机上进行渐进运动方案(30%VO _(2max),50%VO _(2max),70%VO _(2max)),并以45?s的被动休息间隔进行采血。结果血浆葡萄糖氧化与运动强度有关,但在AP组中更大。游离脂肪酸的血浆水平随运动强度的增加而降低,但在特定表型方面具有不同的动力学。停止运动后,血浆生长激素增加,并且与静止值相比,所有组在恢复45分钟后均显着升高。在所有运动期间,血浆胰岛素均下降,但在OP中,下降减少了。结论结果表明,有氧运动的脂解,激素和代谢反应的速率取决于个体的表型。因此,必须严格按照表型对运动类型,持续时间和强度进行个性化设置,以达到最佳的代谢效果。

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