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Does magnetically assisted capsule endoscopy improve small bowel capsule endoscopy completion rate? A randomised controlled trial

机译:磁辅助胶囊内窥镜检查能否提高小肠胶囊内窥镜检查的完成率?随机对照试验

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Background and study aims: Delayed gastric emptying is a significant factor in incomplete small bowel capsule examinations. Gastric transit could be hastened by external magnetic control of the capsule. We studied the feasibility of this approach to improve capsule endoscopy completion rates. Patients and methods: Prospective, single-center, randomized controlled trial involving 122 patients attending for small bowel capsule endoscopy using MiroCam Navi. Patients were randomized to either the control group (mobilisation for 30 minutes after capsule ingestion, followed by intramuscular metoclopramide 10?mg if the capsule failed to enter the small bowel) or the intervention group (1000?mL of water prior to capsule ingestion, followed by positional change and magnetic steering). Outcome measures were capsule endoscopy completion rate, gastric clarity and distention, relationship of body habitus to capsule endoscopy completion rate (CECR), and patient comfort scores. Results: 122 patients were recruited (61 each to the control and intervention groups: mean age 49 years [range 21?–?85], 61 females). There was no significant difference in CECR between the two groups (P?=?0.39). Time to first pyloric image was significantly shorter in the intervention group (P?=?0.03) but there was no difference in gastric transit times (P?=?0.12), suggesting that magnetic control hastens capsular transit to the gastric antrum but does not influence duodenal passage. Gastric clarity and distention were significantly better in the intervention group (P?
机译:背景与研究目的:胃排空延迟是小肠胶囊检查不完全的重要因素。胶囊的外部磁性控制可以加快胃的转运。我们研究了这种方法提高胶囊内窥镜检查完成率的可行性。患者和方法:前瞻性,单中心,随机对照试验,涉及122名使用MiroCam Navi进行小肠胶囊内镜检查的患者。患者被随机分为对照组(胶囊摄入后动员30分钟,如果胶囊无法进入小肠,则肌注甲氧氯普胺10?mg)或干预组(胶囊摄入前1000?mL水)通过位置变化和电磁转向)。结果指标包括胶囊内窥镜检查完成率,胃部清晰度和膨胀度,身体习性与胶囊内窥镜检查完成率(CECR)的关系以及患者舒适度评分。结果:共招募了122例患者(对照组和干预组各61例:平均年龄49岁[21-85岁之间,女性61岁)。两组之间的CECR差异无统计学意义(P = 0.39)。干预组首次幽门造影的时间显着缩短(P = 0.03),但胃转运时间无差异(P = 0.12),表明磁控加速了囊膜向胃窦的转运,但没有影响十二指肠通道。干预组的胃部清澈度和膨胀度明显更好(分别为P 0.0001和P 0.0001)。结论:小肠胶囊的电磁操纵无法克服幽门收缩,从而增强胃排空和提高胶囊内窥镜的完成率。胃腔内出色的粘膜可视化表明该技术可用于胃的胶囊检查。

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