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Development and validation of an automated algorithm to evaluate the abundance of bubbles in small bowel capsule endoscopy

机译:开发和验证用于评估小肠胶囊内窥镜检查中气泡丰富度的自动算法

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Background and study aims Bubbles can impair visualization of the small bowel (SB) mucosa during capsule endoscopy (CE). We aimed to develop and validate a computed algorithm that would allow evaluation of the abundance of bubbles in SB-CE still frames. Patients and methods Two sets of 200 SB-CE normal still frames were created. Two experienced SB-CE readers analyzed both sets of images twice, in a random order. Each still frame was categorized as presenting with Results Both SURF and GLCM algorithms had high operating points (Se and Sp over 90?%) and a perfect reproducibility (κ?=?1). The validation step showed the GLCM detector strategy had the best diagnostic performances, with a Se of 95.79?%, a Sp of 95.19?%, and a calculation time of 0.037 seconds per frame. Conclusion A computed algorithm based on a GLCM detector strategy had high diagnostic performance allowing assessment of the abundance of bubbles in SB-CE still frames. This algorithm could be of interest for clinical use (quality reporting) and for research purposes (objective comparison tool of different preparations).
机译:背景和研究目的气泡会损害胶囊内窥镜检查(CE)期间小肠(SB)粘膜的可视化。我们旨在开发和验证一种计算算法,该算法可以评估SB-CE静止帧中的大量气泡。患者和方法创建了两套200 SB-CE正常静止框架。两位经验丰富的SB-CE读者以随机顺序分析了两组图像两次。每个静止帧都归类为呈现结果。SURF和GLCM算法均具有较高的工作点(Se和Sp均超过90%)和完美的可重复性(κ== 1)。验证步骤表明GLCM检测器策略具有最佳的诊断性能,Se为95.79%,Sp为95.19%,计算时间为每帧0.037秒。结论基于GLCM检测器策略的计算算法具有较高的诊断性能,可以评估SB-CE静止帧中的大量气泡。该算法可能对临床使用(质量报告)和研究目的(不同制剂的客观比较工具)很感兴趣。

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